Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Understanding Cannabis sativa L.: Current Status of Propagation, Use, Legalization, and Haploid-Inducer-Mediated Genetic Engineering

DC Simiyu, JH Jang, OR Lee - Plants, 2022 - mdpi.com
Cannabis sativa L. is an illegal plant in many countries. The worldwide criminalization of the
plant has for many years limited its research. Consequently, understanding the full scope of …

Rates and correlates of cannabis-associated psychotic symptoms in over 230,000 people who use cannabis

T Schoeler, J Ferris, AR Winstock - Translational psychiatry, 2022 - nature.com
Cannabis, a widely used psychoactive substance, can trigger acute cannabis-associated
psychotic symptoms (CAPS) in people who use cannabis (PWUC). To assess rates and …

[HTML][HTML] Gender differences in the association between environment and psychosis

AY Pence, LK Pries, M Ferrara, BPF Rutten… - Schizophrenia …, 2022 - Elsevier
Various environmental exposures have been associated with psychosis spectrum disorder.
However, the role of gender in this association has received little attention. Therefore, we …

Adolescent cannabis use and later development of schizophrenia: An updated systematic review of longitudinal studies

SL Godin, S Shehata - Journal of Clinical Psychology, 2022 - Wiley Online Library
Background The study aimed to review recent literature not included in previous reviews
and ascertain the correlation between early marijuana use among adolescents, between 12 …

The CannTeen Study: Cannabis use disorder, depression, anxiety, and psychotic-like symptoms in adolescent and adult cannabis users and age-matched controls

W Lawn, C Mokrysz, R Lees, K Trinci… - Journal of …, 2022 - journals.sagepub.com
Background: Adolescence is characterised by psychological and neural development.
Cannabis harms may be accentuated during adolescence. We hypothesised that …

North American prodrome longitudinal study (NAPLS 3): methods and baseline description

J Addington, L Liu, K Brummitt, CE Bearden… - Schizophrenia …, 2022 - Elsevier
Abstract The North American Prodrome Longitudinal Study (NAPLS) is a consortium of nine
programs focusing on youth at clinical high risk (CHR) for psychosis. Funded by the National …

Gut–microbiota–brain axis in the vulnerability to psychosis in adulthood after repeated cannabis exposure during adolescence

X Wan, A Eguchi, Y Qu, Y Yang, L Chang… - European Archives of …, 2022 - Springer
Increasing epidemiological evidence shows that the use of cannabis during adolescence
could increase the risk for psychosis in adulthood. However, the precise mechanisms …

High prevalence and early onsets: legal and illegal substance use in an urban cohort of young adults in Switzerland

BB Quednow, A Steinhoff, L Bechtiger… - European addiction …, 2022 - karger.com
Introduction: Debates about the legalization of illegal substances (eg, cannabis) continue
around the globe. A key consideration in these debates is the adequate protection of young …

Thalamocortical development: a neurodevelopmental framework for schizophrenia

LJ Benoit, S Canetta, C Kellendonk - Biological psychiatry, 2022 - Elsevier
Adolescence is a period of increased vulnerability for the development of psychiatric
disorders, including schizophrenia. The prefrontal cortex (PFC) undergoes substantial …