[HTML][HTML] Endogenous opioid systems alterations in pain and opioid use disorder

JA Higginbotham, T Markovic, N Massaly… - Frontiers in systems …, 2022 - frontiersin.org
Decades of research advances have established a central role for endogenous opioid
systems in regulating reward processing, mood, motivation, learning and memory …

[PDF][PDF] The analysis of pain research through the lens of artificial intelligence and machine learning

JN Nagireddi, AK Vyas, MR Sanapati… - Pain …, 2022 - painphysicianjournal.com
Background: Traditional pain assessment methods have significant limitations due to the
high variability in patient reported pain scores and perception of pain by different individuals …

Development of an electrochemical fentanyl nanosensor based on MWCNT-HA/Cu-H3BTC nanocomposite

M Akbari, MS Mohammadnia, M Ghalkhani… - Journal of Industrial and …, 2022 - Elsevier
Fentanyl is a potent narcotic drug with the same effects as morphine or heroin, but it's
significantly more potent than these drugs. That means a tiny dose can have a dangerous …

[PDF][PDF] Evaluation of the effectiveness of autologous bone marrow mesenchymal stem cells in the treatment of chronic low back pain due to severe lumbar spinal …

S Atluri, MB Muy, R Dragella, J Herrera… - Pain …, 2022 - apexbiologix.com
Background: Regenerative medicine interventions are applied to assist in the repair, and to
potentially replace or restore damaged tissue through the use of autologous/allogenic …

[PDF][PDF] COVID-19 pandemic reduced utilization of interventional techniques 18.7% in managing chronic pain in the Medicare population in 2020: analysis of utilization …

L Manchikanti, V Pampati, MR Sanapati… - Pain …, 2022 - painphysicianjournal.com
Background: Multiple publications have shown the significant impact of the COVID-19
pandemic on US healthcare and increasing costs over the recent years in managing low …

[HTML][HTML] Electroanalysis of fentanyl and its new analogs: a review

MK Choińska, I Šestáková, V Hrdlička, J Skopalová… - Biosensors, 2022 - mdpi.com
The review describes fentanyl and its analogs as new synthetic opioids and the possibilities
of their identification and determination using electrochemical methods (eg, voltammetry …

Current Perspectives on Selective Dopamine D3 Receptor Antagonists/Partial Agonists as Pharmacotherapeutics for Opioid and Psychostimulant Use Disorders

AH Newman, ZX Xi, C Heidbreder - … Function: New Insight After 30 Years …, 2022 - Springer
Over three decades of evidence indicate that dopamine (DA) D3 receptors (D3R) are
involved in the control of drug-seeking behavior and may play an important role in the …

[PDF][PDF] A pilot study implementing a machine learning algorithm to use artificial intelligence to diagnose spinal conditions

A Soin, M Hirschbeck, M Verdon… - Pain …, 2022 - painphysicianjournal.com
Background: Chronic spinal pain is the most prevalent chronic disease, with chronic
persistent spinal pain lasting longer than one-year reported in 25% to 60% of the patients …

[PDF][PDF] Impact of COVID-19 pandemic and updated utilization patterns of sacroiliac joint injections from 2000 to 2020 in the fee-for-service (FFS) Medicare population

L Manchikanti, TT Simopoulos, V Pampati… - Pain …, 2022 - painphysicianjournal.com
Background: Among the multiple causes of low back and lower extremity pain, sacroiliac
joint pain has shown to be prevalent in 10% to 25% of patients with persistent axial low back …

International trends in prescription opioid sales among developed and developing economies, and the impact of the COVID‐19 pandemic: a cross‐sectional analysis …

T Gomes, K Callaway Kim, KJ Suda… - … and drug safety, 2022 - Wiley Online Library
Purpose We sought to compare trends in opioid purchasing between developed and
developing economies to understand patterns of opioid consumption, and how they were …