[HTML][HTML] Inhibition of the main protease of SARS-CoV-2 (Mpro) by repurposing/designing drug-like substances and utilizing nature's toolbox of bioactive compounds
I Antonopoulou, E Sapountzaki, U Rova… - Computational and …, 2022 - Elsevier
The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells
Abstract Coronavirus disease 2019 (COVID-19) initiated in December 2019 in Wuhan,
China and became pandemic causing high fatality and disrupted normal life calling world …
China and became pandemic causing high fatality and disrupted normal life calling world …
Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic …
The ongoing COVID-19 pandemic has affected millions of people worldwide and caused
substantial socio-economic losses. Few successful vaccine candidates have been approved …
substantial socio-economic losses. Few successful vaccine candidates have been approved …
Structure and dynamics of membrane protein in SARS-CoV-2
Abstract SARS-CoV-2 membrane (M) protein performs a variety of critical functions in virus
infection cycle. However, the expression and purification of membrane protein structure is …
infection cycle. However, the expression and purification of membrane protein structure is …
[HTML][HTML] Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the …
Objective: Despite the development of several vaccines against severe acute respiratory
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
Identification of potential inhibitors of SARS-CoV-2 main protease and spike receptor from 10 important spices through structure-based virtual screening and …
The outbreak of novel coronavirus disease (COVID-19) caused by SARS-CoV-2 poses a
serious threat to human health and world economic activity. There is no specific drug for the …
serious threat to human health and world economic activity. There is no specific drug for the …
Molecular docking and simulation studies of natural compounds of Vitex negundo L. against papain-like protease (PLpro) of SARS CoV-2 (coronavirus) to conquer …
The severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) is β-coronavirus that is
responsible for the pandemic coronavirus disease 2019 (COVID-19) all over the world. The …
responsible for the pandemic coronavirus disease 2019 (COVID-19) all over the world. The …
Andrographolide Induces anti-SARS-CoV-2 Response Through host-directed Mechanism: an in silico Study
Aim: Considering the present alarming situation of COVID-19 pandemic, we concentrated on
evaluating the efficacy of a novel natural antiviral drug-candidate andrographolide against …
evaluating the efficacy of a novel natural antiviral drug-candidate andrographolide against …
In-silico screening of plant-derived antivirals against main protease, 3CLpro and endoribonuclease, NSP15 proteins of SARS-CoV-2
Abstract Novel Coronavirus or SARS-CoV-2 outbreak has developed a pandemic condition
all over the world. The virus is highly infectious and spreads by human to human local …
all over the world. The virus is highly infectious and spreads by human to human local …