Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes
J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …
[HTML][HTML] Emerging SARS-CoV-2 variants: Why, how, and what's next?
The emergence of the SARS-CoV-2 Omicron variant poses a striking threat to human
society. More than 30 mutations in the Spike protein of the Omicron variant severely …
society. More than 30 mutations in the Spike protein of the Omicron variant severely …
[HTML][HTML] Molecular basis of receptor binding and antibody neutralization of Omicron
Q Hong, W Han, J Li, S Xu, Y Wang, C Xu, Z Li, Y Wang… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant exhibits striking immune evasion and is
spreading rapidly worldwide. Understanding the structural basis of the high transmissibility …
spreading rapidly worldwide. Understanding the structural basis of the high transmissibility …
Omicron BA. 2 breakthrough infection enhances cross-neutralization of BA. 2.12. 1 and BA. 4/BA. 5
A Muik, BG Lui, M Bacher, AK Wallisch, A Toker… - Science …, 2022 - science.org
BNT162b2-vaccinated individuals after Omicron BA. 1 breakthrough infection have strong
serum-neutralizing activity against Omicron BA. 1, BA. 2, and previous SARS-CoV-2 variants …
serum-neutralizing activity against Omicron BA. 1, BA. 2, and previous SARS-CoV-2 variants …
Structural plasticity and immune evasion of SARS-CoV-2 spike variants
The global pandemic of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has significantly affected every human life and overloaded the …
coronavirus 2 (SARS-CoV-2) has significantly affected every human life and overloaded the …
Non-Hermitian many-body localization with open boundaries
The explorations of non-Hermiticity have been devoted to investigate the disorder-induced
many-body localization (MBL). However, the sensitivity of the spatial boundary conditions …
many-body localization (MBL). However, the sensitivity of the spatial boundary conditions …
Disorder-induced topological state transition in the optical skyrmion family
Skyrmions endowed with topological protection have been extensively investigated in
various platforms including magnetics, ferroelectrics, and liquid crystals, stimulating …
various platforms including magnetics, ferroelectrics, and liquid crystals, stimulating …
Borneol ester derivatives as entry inhibitors of a wide spectrum of SARS-CoV-2 viruses
OI Yarovaya, DN Shcherbakov, SS Borisevich… - Viruses, 2022 - mdpi.com
In the present work we studied the antiviral activity of the home library of monoterpenoid
derivatives using the pseudoviral systems of our development, which have glycoproteins of …
derivatives using the pseudoviral systems of our development, which have glycoproteins of …
From the Wuhan-Hu-1 strain to the XD and XE variants: is targeting the SARS-CoV-2 spike protein still a pharmaceutically relevant option against COVID-19?
Since the outbreak of the COVID-19 pandemic in December 2019, the SARS-CoV-2
genome has undergone several mutations. The emergence of such variants has resulted in …
genome has undergone several mutations. The emergence of such variants has resulted in …
Probing mechanisms of binding and allostery in the SARS-CoV-2 spike omicron variant complexes with the host receptor: revealing functional roles of the binding …
G Verkhivker, S Agajanian, R Kassab… - International Journal of …, 2022 - mdpi.com
In this study, we performed all-atom MD simulations of RBD–ACE2 complexes for BA. 1, BA.
1.1, BA. 2, and BA. 3 Omicron subvariants, conducted a systematic mutational scanning of …
1.1, BA. 2, and BA. 3 Omicron subvariants, conducted a systematic mutational scanning of …