Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

[HTML][HTML] A systematic review of vaccine breakthrough infections by SARS-CoV-2 delta variant

M Zhang, Y Liang, D Yu, B Du, W Cheng… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Vaccines are proving to be highly effective in controlling hospitalization and deaths
associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19

C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …

PWM2Vec: An efficient embedding approach for viral host specification from coronavirus spike sequences

S Ali, B Bello, P Chourasia, RT Punathil, Y Zhou… - Biology, 2022 - mdpi.com
Simple Summary The family of coronaviruses comprises a diverse set of strains and variants
which cause diseases from the common cold to COVID-19. Moreover, they infect a wide …

Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms

A Jafari, F Danesh Pouya, Z Niknam… - Molecular biology …, 2022 - Springer
The world is grappling with an unprecedented public health crisis COVID-19 pandemic
caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates …

Inflammatory mediators profile in patients hospitalized with COVID-19: A comparative study

A Tufa, TH Gebremariam, T Manyazewal… - Frontiers in …, 2022 - frontiersin.org
Abnormal inflammatory mediator concentrations during SARS-CoV-2 infection may
represent disease severity. We aimed to assess plasma inflammatory mediator …

Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge

H Li, X Li, Q Wu, X Wang, Z Qin, Y Wang, Y He… - Cell Death & …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) has gained prominence as a global
pandemic. Studies have suggested that systemic alterations persist in a considerable …

Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

Impact of national COVID-19 restrictions on incidence of notifiable communicable diseases in England: an interrupted time series analysis

K Nash, J Lai, K Sandhu, JS Chandan… - BMC Public Health, 2022 - Springer
Abstract Background Non-pharmaceutical interventions (NPIs), such as travel restrictions,
social distancing and isolation policies, aimed at controlling the spread of COVID-19 may …

Reverse transcription-loop-mediated isothermal amplification-CRISPR-Cas13a technology as a promising diagnostic tool for SARS-CoV-2

C Ortiz-Cartagena, L Fernández-García… - Microbiology …, 2022 - Am Soc Microbiol
At the end of 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), caused a pandemic that persists to date and has resulted in more than 6.2 …