[HTML][HTML] The pathobiology of myalgic encephalomyelitis/chronic fatigue syndrome: the case for neuroglial failure

H Renz-Polster, ME Tremblay, D Bienzle… - Frontiers in cellular …, 2022 - frontiersin.org
Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and
distinctive profile of clinical features, the disease remains an enigma because causal …

Melatonin induces fat browning by transdifferentiation of white adipocytes and de novo differentiation of mesenchymal stem cells

D Salagre, M Chayah, A Molina-Carballo… - Food & Function, 2022 - pubs.rsc.org
The role of melatonin in obesity control is extensively accepted, but its mechanism of action
is still unclear. Previously we demonstrated that chronic oral melatonin acts as a brown-fat …

DNA methylation alterations in fractionally irradiated rats and breast cancer patients receiving radiotherapy

M Sallam, M Mysara, MA Benotmane… - International journal of …, 2022 - mdpi.com
Radiation-Induced CardioVascular Disease (RICVD) is an important concern in thoracic
radiotherapy with complex underlying pathophysiology. Recently, we proposed DNA …

Modulation of Inflammatory Signaling Molecules in Bordetella pertussis Antigen-Challenged Human Monocytes in Presence of Adrenergic Agonists

MO Raihan, BM Espelien, BA McGregor, C Hanson… - Vaccines, 2022 - mdpi.com
BscF is a type III secretion system (T3SS) needle protein from Bordetella pertussis and has
previously been shown to induce a sufficient Th1 and Th17 response in human monocytes …

Chlamydia trachomatis Requires Functional Host-Cell Mitochondria and NADPH Oxidase 4/p38MAPK Signaling for Growth in Normoxia

J Thapa, G Yoshiiri, K Ito, T Okubo… - Frontiers in cellular …, 2022 - frontiersin.org
Chlamydia trachomatis (Ct) is an intracellular energy-parasitic bacterium that requires ATP
derived from infected cells for its growth. Meanwhile, depending on the O2 concentration …

Integrative identification of genetic loci jointly influencing diabetes-related traits and sleep traits of insomnia, sleep duration, and chronotypes

Y Ma, Z Zhou, X Li, Z Yan, K Ding, H Xiao, Y Wu, T Wu… - Biomedicines, 2022 - mdpi.com
Accumulating evidence suggests a relationship between type 2 diabetes mellitus and sleep
problems. A comprehensive study is needed to decipher whether shared polygenic risk …

Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells

P Türck, A Nemec-Bakk, T Talwar, Z Suntres… - Molecular and Cellular …, 2022 - Springer
Enhanced sympathetic system activation mediated by norepinephrine (NE) contributes to
adverse cardiac remodeling leading to oxidative stress and cell death, progressing to heart …

The role of Nrf2/SIRT1 pathway in the hepatoprotective effect of PEITC against HFD/STZ-induced diabetic liver disease

B Atici, AB Uyumlu, A Taslidere - 2022 - annalsmedres.org
Aim: We intended to assess the hepatoprotective effects of phenethyl isothiocyanate (PEITC)
against oxidative liver injury induced by a high-fat diet (HFD) and streptozotocin (STZ) …

Melatonin induces fat browning by transdifferentiation of white adipocytes and de novo differentiation of mesenchymal stem cells

D Salagre Simón, M Chayah Ghaddab… - 2022 - digibug.ugr.es
The role of melatonin in obesity control is extensively accepted, but its mechanism of action
is still unclear. Previously we demonstrated that chronic oral melatonin acts as a brown-fat …

Arrhythmia mechanisms and effects of exercise training in CPVT and post-infarction heart failure

TK Danielsen - 2022 - duo.uio.no
Regular physical activity protects against cardiovascular disease. However, exercise can
provoke fatal heart rhythm disturbances in some conditions. Patients with heart failure have …