The roles of Par3, Par6, and aPKC polarity proteins in normal neurodevelopment and in neurodegenerative and neuropsychiatric disorders
L Zhang, X Wei - Journal of Neuroscience, 2022 - Soc Neuroscience
Normal neural circuits and functions depend on proper neuronal differentiation, migration,
synaptic plasticity, and maintenance. Abnormalities in these processes underlie various …
synaptic plasticity, and maintenance. Abnormalities in these processes underlie various …
Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes
The genetic locus containing the WWOX and MAF genes was implicated as a clinical
Alzheimer's disease (AD) risk locus in two recent large meta-analytic genome wide …
Alzheimer's disease (AD) risk locus in two recent large meta-analytic genome wide …
Genetic association study reveals impact of interleukin 10 polymorphisms on cognitive functions in schizophrenia
P Zakowicz, J Pawlak, P Kapelski… - Behavioural Brain …, 2022 - Elsevier
Aim Cognitive deficits are the core factors impacting quality of life among patients diagnosed
with schizophrenia. Effective method of treatment for this domain of symptoms remains …
with schizophrenia. Effective method of treatment for this domain of symptoms remains …
Pharmacogenetics of psychotropic drugs and genetic influences on adverse drug reactions
I Austin-Zimmerman - 2022 - discovery.ucl.ac.uk
In this thesis, I investigate the impact of genetic variation on adverse drug reactions to
psychotropic medications, with a focus on the metabolic and sleep related side effects of …
psychotropic medications, with a focus on the metabolic and sleep related side effects of …
Investigations into the Genetics of Mixed Pathologies in Dementia
A Dugan - uknowledge.uky.edu
Alzheimer's disease (AD) is an irreversible, progressive brain disorder that leads to a loss of
memory and thinking skills. While tremendous progress has been made in our …
memory and thinking skills. While tremendous progress has been made in our …
Method for predicting the response of antipsychotic drugs
S Jamain, R Troudet - US Patent App. 17/606,099, 2022 - Google Patents
(57) ABSTRACT A fundamental shortcoming in the current treatment of schizophrenia is the
lack of valid criteria to predict who will respond to antipsychotic treatment. The identification …
lack of valid criteria to predict who will respond to antipsychotic treatment. The identification …