Post-vaccination T cell immunity to omicron

H Jacobsen, V Cobos Jiménez, I Sitaras… - Frontiers in …, 2022 - frontiersin.org
In late 2021, the omicron variant of SARS Coronavirus 2 (SARS-CoV-2) emerged and
replaced the previously dominant delta strain. Effectiveness of COVID-19 vaccines against …

[HTML][HTML] The humoral and cellular immune evasion of SARS-CoV-2 Omicron and sub-lineages

T Xiang, J Wang, X Zheng - Virologica Sinica, 2022 - Elsevier
The recently discovered SARS-CoV-2 variant Omicron (B. 1.1. 529) has rapidly become a
global public health issue. The substantial mutations in the spike protein in this new variant …

Clinical characteristics of COVID-19 patients infected by the Omicron variant of SARS-CoV-2

J Zhang, N Chen, D Zhao, J Zhang, Z Hu… - Frontiers in medicine, 2022 - frontiersin.org
Background Currently, as the omicron variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) surges amid the coronavirus disease 2019 (COVID-19) …

SARS-CoV-2 infection and vaccination trigger long-lived B and CD4+ T lymphocytes with implications for booster strategies

A Mazzoni, A Vanni, M Spinicci… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Immunization against SARS-CoV-2, the causative agent of COVID-19,
occurs via natural infection or vaccination. However, it is currently unknown how long …

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

D Mrak, D Sieghart, E Simader, S Tobudic… - Nature …, 2022 - nature.com
Impaired response to COVID-19 vaccination is of particular concern in immunosuppressed
patients. To determine the best vaccination strategy for this vulnerable group we performed …

Need of booster vaccine doses to counteract the emergence of SARS-CoV-2 variants in the context of the Omicron variant and increasing COVID-19 cases: An update

RK Mohapatra, NA El-Shall, R Tiwari… - Human Vaccines & …, 2022 - Taylor & Francis
The emergence of different variants of SARS-CoV-2, including the Omicron (B. 1.1. 529)
variant in November 2021, has resulted in a continuous major health concern at a global …

Clinical and immunological features of SARS-CoV-2 breakthrough infections in vaccinated individuals requiring hospitalization

G Lamacchia, A Mazzoni, M Spinicci, A Vanni… - Journal of Clinical …, 2022 - Springer
Abstract Background and Purpose Waning immunity and the surge of SARS-CoV-2 variants
are responsible for breakthrough infections, ie, infections in fully vaccinated individuals …

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules

S Nersisyan, A Zhiyanov, M Zakharova, I Ishina… - PeerJ, 2022 - peerj.com
The T-cell immune response is a major determinant of effective SARS-CoV-2 clearance.
Here, using the recently developed T-CoV bioinformatics pipeline (https://t-cov. hse. ru) we …

CD8+ T-cell immune escape by SARS-CoV-2 variants of concern

AJ Kombe Kombe, FAN Biteghe… - Frontiers in …, 2022 - frontiersin.org
Despite the efficacy of antiviral drug repositioning, convalescent plasma (CP), and the
currently available vaccines against severe acute respiratory syndrome coronavirus 2 …

Cellular therapies for the treatment and prevention of SARS-CoV-2 infection

SR Conway, MD Keller… - Blood, The Journal of the …, 2022 - ashpublications.org
Patients with blood disorders who are immune suppressed are at increased risk for infection
with severe acute respiratory syndrome coronavirus 2. Sequelae of infection can include …