Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Fibrosis disrupts adipose tissue (AT) homeostasis and exacerbates metabolic dysfunction
upon chronic caloric excess. The molecular mechanisms linking adipocyte plasticity to AT …

Cultured meat is an emergent technology with the potential for significant environmental and
animal welfare benefits. Accurate mimicry of traditional meat requires fat tissue; a key …

The obesity pandemic is presumed to be accelerated by endocrine disruptors such as
phthalate-plasticizers, which interfere with adipose tissue function. With the restriction of the …

Healthy adipose tissue remodeling depends on the balance between de novo adipogenesis
from adipogenic progenitor cells and the hypertrophy of adipocytes. De novo adipogenesis …

The peroxisome proliferator-activated receptor PPAR-γ is one of three PPAR nuclear
receptors that act as ligand-activated transcription factors. In immune cells, the skin, and …

Obesity and its' associated metabolic diseases such as type 2 diabetes and cardiometabolic
disorders are significant health problems confronting many countries. A major driver for …

Persistent organic pollutants (POPs) are considered as potential obesogens that may affect
adipose tissue development and functioning, thus promoting obesity. However, various …

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that is a vital
regulator of adipogenesis, insulin sensitivity, and lipid metabolism. Activation of PPARγ by …