Antibacterial and Anticancer Activities of Pleurocidin-Amide, a Potent Marine Antimicrobial Peptide Derived from Winter Flounder, Pleuronectes americanus

HC Hsu, MH Chen, ML Yeh, WJ Chen - Marine Drugs, 2022 - mdpi.com
The extensive use of conventional antibiotics has led to the growing emergence of many
resistant strains of pathogenic bacteria. Evidence suggests that cationic antimicrobial …

Temporin B forms hetero-oligomers with temporin L, modifies its membrane activity, and increases the cooperativity of its antibacterial pharmacodynamic profile

PM Ferguson, M Clarke, G Manzo, CK Hind… - Biochemistry, 2022 - ACS Publications
The pharmacodynamic profile of antimicrobial peptides (AMPs) and their in vivo synergy are
two factors that are thought to restrict resistance evolution and ensure their conservation …

[PDF][PDF] Magainin 2 and PGLa in bacterial membrane mimics IV: Membrane curvature and partitioning

EF Semeraro, P Pajtinka, L Marx, I Kabelka, R Leber… - Biophysical …, 2022 - cell.com
We previously reported that the synergistically enhanced antimicrobial activity of magainin 2
(MG2a) and PGLa is related to membrane adhesion and fusion. Here, we demonstrate that …

Beehives as a natural source of novel antimicrobials

J Suran - Promising Antimicrobials from Natural Products, 2022 - Springer
Honey bee products have been used since ancient times as food and therapeutics. There is
increasing knowledge on their content and molecular mechanism of action. Their bioactive …

Development of a novel zein-derived peptide: in vitro assays, and 2D-and 3D-cell models

PA Trinidad Calderón - 2022 - repositorio.tec.mx
Maize is the most consumed staple crop worldwide. Its composition, abundant in prolamins
corresponding to α-zein, represents an opportunity for the search of bioactive candidates …

Role of lipopolysaccharide in membrane-active-peptide interactions with cells as probed by whole-cell deuterium NMR

S Kumari - 2022 - research.library.mun.ca
The increasing appearance of multidrug-resistant pathogens has created an urgent need for
suitable alternatives to current antibiotics. Antimicrobial peptides (AMPs), which act as …