Cryptococcus neoformans infections cause approximately 15% of AIDS-related deaths
owing to a combination of limited antifungal therapies and drug resistance. A collection of …

The yeast SKI (superkiller) complex was originally identified from cells that were infected by
the M 'killer'virus. Ski2, as the core of the SKI complex, is a cytoplasmic cofactor and …

Genetic manipulation for generating knock‐out experiments is essential in deciphering the
precise function of a gene. However, dikaryotic fungi pose the inherent challenge of having …

RNA 干扰(RNA interference, RNAi) 是一种保守的真核生物基因调控机制,
它利用小的非编码RNA 介导转录/转录后的基因沉默. 虽然部分真菌丢失了RNAi 系统 …

Simple Summary RNA silencing in fungi was shown to confer antiviral defense against plant
viruses. In this study, using high-throughput sequencing and bioinformatic analyses, we …

S5. 3 Cellular pleomorphism and fungal virulence, September 22, 2022, 3: 00 PM-4: 30 PM
Cryptococcus neoformans is a human pathogenic basidiomycete yeast that can cause …

The basidiomycete yeasts from the Cryptococcus neoformans/gattii species complex are
major fungal pathogens and are particularly prevalent in the developing world. The species …

My thesis work has focused on characterizing mechanisms by which human fungal
pathogens regulate their adaptive cellular responses in order to survive and cause disease …

Microorganisms must regulate genomic stability to strike a balance between excessive
deleterious mutation and evolutionary stagnation to successfully compete and endure within …

The biological function of RNAi machinery in fungi appears puzzling. In yeast Cryptococcus
neoformans, we observed that RNAi-deficient mutants displayed diminished ribosome …