World Stroke Organization (WSO): global stroke fact sheet 2022

VL Feigin, M Brainin, B Norrving… - … Journal of Stroke, 2022 - journals.sagepub.com
Stroke remains the second-leading cause of death and the third-leading cause of death and
disability combined (as expressed by disability-adjusted life-years lost–DALYs) in the world …

Primary stroke prevention worldwide: translating evidence into action

MO Owolabi, AG Thrift, A Mahal, M Ishida… - The Lancet Public …, 2022 - thelancet.com
Stroke is the second leading cause of death and the third leading cause of disability
worldwide and its burden is increasing rapidly in low-income and middle-income countries …

Stroke genetics informs drug discovery and risk prediction across ancestries

A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba… - Nature, 2022 - nature.com
Previous genome-wide association studies (GWASs) of stroke—the second leading cause of
death worldwide—were conducted predominantly in populations of European ancestry …

Effect of stenting plus medical therapy vs medical therapy alone on risk of stroke and death in patients with symptomatic intracranial stenosis: the CASSISS …

P Gao, T Wang, D Wang, DS Liebeskind, H Shi, T Li… - Jama, 2022 - jamanetwork.com
Importance Prior randomized trials have generally shown harm or no benefit of stenting
added to medical therapy for patients with symptomatic severe intracranial atherosclerotic …

Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019

C Ding, Y Wu, X Chen, Y Chen, Z Wu, Z Lin… - Frontiers in public …, 2022 - frontiersin.org
Background Neurological disorders are a major and increasing global health challenge,
which accounts for a substantial portion of the disease burden worldwide. The aim of this …

Systemic inflammation after stroke: implications for post‐stroke comorbidities

A Simats, A Liesz - EMBO molecular medicine, 2022 - embopress.org
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion

Q Tuo, Y Liu, Z Xiang, HF Yan, T Zou, Y Shu… - Signal transduction and …, 2022 - nature.com
Ischemic stroke represents a significant danger to human beings, especially the elderly.
Interventions are only available to remove the clot, and the mechanism of neuronal death …

Global, regional, and national burden of ischemic stroke, 1990–2019

Q Ding, S Liu, Y Yao, H Liu, T Cai, L Han - Neurology, 2022 - AAN Enterprises
Background and Objectives To the best of our knowledge, no comprehensive update of the
descriptive epidemiology and trends of ischemic stroke has been released since Global …

Se‐Containing MOF Coated Dual‐Fe‐Atom Nanozymes With Multi‐Enzyme Cascade Activities Protect Against Cerebral Ischemic Reperfusion Injury

R Tian, H Ma, W Ye, Y Li, S Wang… - Advanced Functional …, 2022 - Wiley Online Library
The atomically monodispersed dual‐atom nanozyme not only possesses the advantages of
homogeneous active centers and high atomic utilization efficiency but also exhibits amazing …

Report on cardiovascular health and diseases in China 2021: an updated summary

TWC of the Report - Biomedical and Environmental Sciences, 2022 - Elsevier
Abstract In 2019, cardiovascular disease (CVD) accounted for 46.74% and 44.26% of all
deaths in rural and urban areas, respectively. Two out of every five deaths were due to CVD …