Inflammaging at the Time of COVID-19

MB Zazzara, A Bellieni, R Calvani… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
Inflammaging and SARS-CoV-2 infection interact in an interplay that involves both acute
inflammation and low-grade chronic inflammation, predisposing older adults to severe …

Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials

A Izcovich, RA Siemieniuk, JJ Bartoszko, L Ge… - BMJ open, 2022 - bmjopen.bmj.com
Background To summarise specific adverse effects of remdesivir, hydroxychloroquine and
lopinavir/ritonavir in patients with COVID-19. Methods We searched 32 databases through …

The role of natural products from medicinal plants against COVID-19: traditional medicine practice in Tanzania

SH Mlozi - Heliyon, 2022 - cell.com
Background Pandemic COVID-19 is a dangerous disease caused by a new coronavirus
known as severe acute respiratory syndrome (SARS-CoV-2). There is non-reliable drug or …

Saving millions of lives but some resources squandered: emerging lessons from health research system pandemic achievements and challenges

SR Hanney, SE Straus, BJ Holmes - Health Research Policy and Systems, 2022 - Springer
During the SARS-CoV-2 pandemic, astonishingly rapid research averted millions of deaths
worldwide through new vaccines and repurposed and new drugs. Evidence use informed …

COVID-19 as another trigger for HBV reactivation: clinical case and review of literature

C Sagnelli, L Montella, P Grimaldi, M Pisaturo… - Pathogens, 2022 - mdpi.com
Universal hepatitis B virus (HBV) vaccination has been applied for years in most countries,
but HBV infection remains an unresolved public health problem worldwide, with over one …

Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID‐19; a systematic review and meta‐analysis of randomized clinical trials

D Vela, Z Vela‐Gaxha, M Rexhepi… - British Journal of …, 2022 - Wiley Online Library
Aims Tocilizumab has emerged as an important therapy in treating patients with coronavirus
disease (COVID‐19). Our purpose was to evaluate the efficacy and safety of tocilizumab …

Long-term functioning status of COVID-19 survivors: a prospective observational evaluation of a cohort of patients surviving hospitalisation

LR Battistella, M Imamura, LR De Pretto… - BMJ open, 2022 - bmjopen.bmj.com
Objectives The study investigated the long-term functional status of hospitalised COVID-19
survivors to explore and document their functional situation. Design This prospective …

Efficacy of Covexir® (Ferula foetida oleo‐gum) treatment in symptomatic improvement of patients with mild to moderate COVID‐19: A randomized, double‐blind …

M Hasanpour, H Safari… - Phytotherapy …, 2022 - Wiley Online Library
Abstract The SARS‐CoV‐2 COVID‐19 pandemic has emerged as an unprecedented
emergency state in healthcare system and global challenge. In recent decade, the function …

The Australian living guidelines for the clinical care of people with COVID-19: what worked, what didn't and why, a mixed methods process evaluation

T Turner, J Elliott, B Tendal, JP Vogel, S Norris… - PLoS …, 2022 - journals.plos.org
Introduction The Australian National COVID-19 Clinical Evidence Taskforce is producing
living, evidence-based, national guidelines for treatment of people with COVID-19 which are …

Construct validity and responsiveness of the COVID-19 Yorkshire Rehabilitation Scale (C19-YRS) in a cohort of Italian hospitalized COVID-19 patients

S Straudi, F Manfredini, A Baroni, G Milani… - International Journal of …, 2022 - mdpi.com
Post-COVID Syndrome (PCS) is characterized by physical, psychological and cognitive
symptoms with a negative impact on daily activities. This study tested the responsiveness …