[HTML][HTML] Signaling pathways in obesity: mechanisms and therapeutic interventions

X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

[HTML][HTML] Recent advances in incretin-based pharmacotherapies for the treatment of obesity and diabetes

Q Tan, SE Akindehin, CE Orsso, RC Waldner… - Frontiers in …, 2022 - frontiersin.org
The incretin hormone glucagon-like peptide-1 (GLP-1) has received enormous attention
during the past three decades as a therapeutic target for the treatment of obesity and type 2 …

[HTML][HTML] Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

[HTML][HTML] Ketone bodies and SIRT1, synergic epigenetic regulators for metabolic health: a narrative review

R Tozzi, F Cipriani, D Masi, S Basciani, M Watanabe… - Nutrients, 2022 - mdpi.com
Ketone bodies (KBs) and Sirtuin-1 (SIRT1) have received increasing attention over the past
two decades given their pivotal function in a variety of biological contexts, including …

Effect of exposure to endocrine disrupting chemicals in obesity and neurodevelopment: The genetic and microbiota link

V Ramírez, P González-Palacios, MA Baca… - Science of The Total …, 2022 - Elsevier
Current evidence highlights the importance of the genetic component in obesity and
neurodevelopmental disorders (attention-deficit hyperactivity disorder (ADHD), autism …

Syndromic and nonsyndromic obesity: underlying genetic causes in humans

J Duis, MG Butler - Advanced Biology, 2022 - Wiley Online Library
Growing evidence supports syndromic and nonsyndromic causes of obesity, including
genome‐wide association studies, candidate gene analysis, advanced genetic technology …

Polysaccharides from edible brown seaweed Undaria pinnatifida are effective against high-fat diet-induced obesity in mice through the modulation of intestinal …

P Zhang, J Jia, P Jiang, W Zheng, X Li, S Song, C Ai - Food & Function, 2022 - pubs.rsc.org
Brown seaweed is rich in polysaccharides including sulfated polysaccharides and alginate,
both of which provide health benefits to the host but whose differences have not received …

[HTML][HTML] Prenatal effects of nicotine on obesity risks: a narrative review

O White, N Roeder, K Blum, RD Eiden… - International journal of …, 2022 - mdpi.com
Nicotine usage by mothers throughout pregnancy has been observed to relate to numerous
deleterious effects in children, especially relating to obesity. Children who have prenatally …

[HTML][HTML] The landscape of the long non-coding RNAs and circular RNAs of the abdominal fat tissues in the chicken lines divergently selected for fatness

Y Jing, B Cheng, H Wang, X Bai, Q Zhang, N Wang… - BMC genomics, 2022 - Springer
Background Excessive deposition of abdominal fat poses serious problems in broilers owing
to rapid growth. Recently, the evolution of the existing knowledge on long non-coding RNAs …

[HTML][HTML] Amelioration of mercuric chloride-induced physiologic and histopathologic alterations in rats using vitamin E and zinc chloride supplement

MG Shalan - Heliyon, 2022 - cell.com
The drastic effects of mercuric chloride and the protective efficiency of vitamin E and zinc
chloride co-supplementation were clearly investigated in this study. Male rats were divided …