Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Ovarian aging refers to the process by which ovarian function declines until eventual failure.
The pathogenesis of ovarian aging is complex and diverse; oxidative stress (OS) is …

Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using
data from large endometriosis and EOC genome-wide association meta-analyses, we …

Many risk factors have been identified for breast cancer. The potential causality for some of
them remains uncertain, and few studies have comprehensively investigated these …

Hip fracture is the clinically most important fracture, but the genetic architecture of hip
fracture is unclear. Here, we perform a large-scale hip fracture genome-wide association …

BACKGROUND DNA damage is a hazard that affects all cells of the body. DNA-damage
repair (DDR) mechanisms are in place to repair damage and restore cellular function, as are …

Background Women's reproductive factors include their age at menarche and menopause,
the age at which they start and stop having children and the number of children they have …

The present study was designed to examine whether sex hormone polymorphisms proven
by GWAS are associated with endometriosis risk. Unrelated female participants totaling …

Background Observational epidemiological studies suggest a link between several factors
related to ovulation and reproductive function and endometrial cancer (EC) risk; however, it …