[HTML][HTML] The role of prefrontal cortex in cognitive control and executive function

NP Friedman, TW Robbins - Neuropsychopharmacology, 2022 - nature.com
Abstract Concepts of cognitive control (CC) and executive function (EF) are defined in terms
of their relationships with goal-directed behavior versus habits and controlled versus …

[HTML][HTML] Development of prefrontal cortex

SM Kolk, P Rakic - Neuropsychopharmacology, 2022 - nature.com
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

[HTML][HTML] Shared mechanisms across the major psychiatric and neurodegenerative diseases

TS Wingo, Y Liu, ES Gerasimov, SM Vattathil… - Nature …, 2022 - nature.com
Several common psychiatric and neurodegenerative diseases share epidemiologic risk;
however, whether they share pathophysiology is unclear and is the focus of our …

Genetic variants associated with longitudinal changes in brain structure across the lifespan

RM Brouwer, M Klein, KL Grasby, HG Schnack… - Nature …, 2022 - nature.com
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …

[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia

C Doust, P Fontanillas, E Eising, SD Gordon, Z Wang… - Nature …, 2022 - nature.com
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …

Genome-wide analyses of individual differences in quantitatively assessed reading-and language-related skills in up to 34,000 people

E Eising, N Mirza-Schreiber… - Proceedings of the …, 2022 - National Acad Sciences
The use of spoken and written language is a fundamental human capacity. Individual
differences in reading-and language-related skills are influenced by genetic variation, with …

Mapping brain asymmetry in health and disease through the ENIGMA consortium

XZ Kong, MC Postema, T Guadalupe… - Human brain …, 2022 - Wiley Online Library
Left–right asymmetry of the human brain is one of its cardinal features, and also a complex,
multivariate trait. Decades of research have suggested that brain asymmetry may be altered …

Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases

C Makowski, D van der Meer, W Dong, H Wang, Y Wu… - Science, 2022 - science.org
To determine the impact of genetic variants on the brain, we used genetically informed brain
atlases in genome-wide association studies of regional cortical surface area and thickness …

A strong dependency between changes in fluid and crystallized abilities in human cognitive aging

EM Tucker-Drob, J De la Fuente, Y Köhncke… - Science …, 2022 - science.org
Theories of adult cognitive development classically distinguish between fluid abilities, which
require effortful processing at the time of assessment, and crystallized abilities, which …

[HTML][HTML] Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network

S Qi, J Sui, G Pearlson, J Bustillo… - Nature …, 2022 - nature.com
Schizophrenia is a highly heritable psychiatric disorder characterized by widespread
functional and structural brain abnormalities. However, previous association studies …