β-Lactams have been a clinical focus since their emergence and indeed act as a powerful
tool to combat severe bacterial infections, but their effectiveness is threatened by drug …

Heterocyclic compounds containing the oxazole, isoxazole and oxadiazoles rings have
received significant consideration as they perform like a link between life sciences and …

Drug-resistant pathogens pose a global challenge to public health as they cause diseases
that are extremely difficult to cure. Metallo-β-lactamases (MBLs) are a diverse set of zinc …

Benzeneseleninic acid was used under visible light irradiation (white LEDs) to promote the
oxidative cyclization of N‐propargyl amides to the respective 2‐substituted oxazole‐5 …

The increasing antibiotic resistance is a clinical problem worldwide. Numerous Gram-
negative bacteria have already become resistant to the most widely used class of …

New Delhi metallo-β-lactamase-1 (NDM-1), expressed in different Gram-negative bacteria,
is a versatile enzyme capable of hydrolyzing β-lactam rings containing antibiotics such as …

Bacteria expressing New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze β-lactam
antibiotics (penicillins, cephalosporins, and carbapenems) and, thus, mediate multidrug …

Antibiotic resistance has been becoming more and more critical due to bacteria's evolving
hydrolysis enzymes. The NDM-1 enzyme could hydrolyze not only carbapenems but also …

Development of phosphorus-containing metallo-β-lactamase inhibitors : Synthesis and
binding studies by solution NMR and molecular docking diva-portal.org Digitala …

Abstract The emergence of New Delhi metallo-beta-lactamase-1 (NDM-1) has conferred
enteric bacteria resistance to almost all beta-lactam antibiotics. Its capability of horizontal …