The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

Climate change is a major global public-health challenge that will have wide-ranging
impacts on human psychological health and well-being. Children and adolescents are at …

People with schizophrenia die 15‐20 years prematurely. Understanding mortality risk and
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …

BackgroundTreatment-resistant schizophrenia (TRS) is associated with high levels of
functional impairment, healthcare usage and societal costs. Cross-sectional studies may …

We mapped the evidence on the type and strength of associations between a broad range of
mental and physical conditions in children and adolescents, by carrying out an umbrella …

Background A huge and still growing mortality gap between people with severe mental
illness (SMI) and the general population exists. Physical illnesses, mainly cardiovascular …

People with severe mental illness (SMI; including schizophrenia/psychosis, bipolar disorder
(BD), major depressive disorder (MDD)) experience large disparities in physical health …

Background Despite increased rates of physical health problems in people with
schizophrenia, bipolar disorder, and other psychotic illnesses, the temporal relationship …

Schizophrenia is frequently associated with obesity, which is linked with neurostructural
alterations. Yet, we do not understand how the brain correlates of obesity map onto the brain …

The excess mortality observed in people with severe mental disorders (SMD) has not
improved over time and is not captured in estimates of disease burden. This study aimed to …