Pulmonary aspergillosis: diagnosis and treatment

F Lamoth, T Calandra - European Respiratory Review, 2022 - Eur Respiratory Soc
Aspergillus species are the most frequent cause of fungal infections of the lungs with a
broad spectrum of clinical presentations including invasive pulmonary aspergillosis (IPA) …

[HTML][HTML] Chest imaging in systemic endemic mycoses

C Sousa, E Marchiori, A Youssef, TL Mohammed… - Journal of Fungi, 2022 - mdpi.com
Endemic fungal infections are responsible for high rates of morbidity and mortality in certain
regions of the world. The diagnosis and management remain a challenge, and the reason …

Efficacy of 12-months oral itraconazole versus 6-months oral itraconazole to prevent relapses of chronic pulmonary aspergillosis: an open-label, randomised …

IS Sehgal, S Dhooria, V Muthu, KT Prasad… - The Lancet Infectious …, 2022 - thelancet.com
Background Chronic pulmonary aspergillosis has a 5-year mortality of 50–80% globally, and
the optimal duration of treatment for chronic pulmonary aspergillosis remains unclear. We …

Azole resistance in Aspergillus fumigatus. The first 2‐year's Data from the Danish National Surveillance Study, 2018–2020

M Risum, RK Hare, JB Gertsen, L Kristensen… - Mycoses, 2022 - Wiley Online Library
Background Azole resistance complicates treatment of patients with invasive aspergillosis
with an increased mortality. Azole resistance in Aspergillus fumigatus is a growing problem …

Chronic pulmonary aspergillosis in patients with active pulmonary tuberculosis with persisting symptoms in Uganda

M Namusobya, F Bongomin, J Mukisa, WK Olwit… - Mycoses, 2022 - Wiley Online Library
Background The occurrence of chronic pulmonary aspergillosis (CPA) among drug sensitive
pulmonary tuberculosis (PTB) patients on optimal therapy with persistent symptoms was …

[HTML][HTML] Efficacy of LD bio Aspergillus ICT lateral flow assay for serodiagnosis of chronic pulmonary aspergillosis

A Ray, M Chowdhury, J Sachdev, P Sethi, VP Meena… - Journal of Fungi, 2022 - mdpi.com
Background: The diagnosis of CPA relies on the detection of the IgG Aspergillus antibody,
which is not freely available, especially in resource-poor settings. Point-of-care tests like …

Chronic pulmonary aspergillosis is common among patients with presumed tuberculosis relapse in Ghana

BK Ocansey, B Otoo, A Adjei, H Gbadamosi… - Medical …, 2022 - academic.oup.com
Chronic pulmonary aspergillosis (CPA) may mimic pulmonary tuberculosis (PTB). The two
diseases are clinically indistinguishable and may result in CPA misdiagnosed as PTB or …

[HTML][HTML] Serological evidence of chronic pulmonary Aspergillosis in tuberculosis patients in Kenya

A Mohamed, BA Obanda, HK Njeri, SN Loroyokie… - BMC Infectious …, 2022 - Springer
Background Pulmonary tuberculosis (PTB) is a significant risk factor for fungal infection. The
cavitary lesions post PTB serves as a good reservoir for fungal colonization and subsequent …

[HTML][HTML] Lung and gut microbiomes in pulmonary aspergillosis: Exploring adjunctive therapies to combat the disease

L Cai, P Gao, Z Wang, C Dai, Y Ning, M Ilkit… - Frontiers in …, 2022 - frontiersin.org
Species within the Aspergillus spp. cause a wide range of infections in humans, including
invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic …

Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement

E Van Braeckel, I Page, JR Davidsen… - European …, 2022 - Eur Respiratory Soc
Chronic pulmonary aspergillosis (CPA) is an uncommon but dreaded complication of many
respiratory diseases occurring in non-or mildly immunocompromised patients [1]. CPA …