There are only a few platforms that integrate multiple omics data types, bioinformatics tools,
and interfaces for integrative analyses and visualization that do not require programming …

Omics mainly includes genomics, epigenomics, transcriptomics, proteomics and
metabolomics. The rapid development of omics technology has opened up new ways to …

Background With the rapid development and wide application of high-throughput
sequencing technology, biomedical research has entered the era of large-scale omics data …

Since the function of a protein is defined by its interaction partners, and since we expect
similar interaction patterns across species, the alignment of protein-protein interaction (PPI) …

As genetic circuits become more sophisticated, the size and complexity of data about their
designs increase. The data captured goes beyond genetic sequences alone; information …

Topological network alignment aims to align two networks node-wise in order to maximize
the observed common connection (edge) topology between them. The topological alignment …

Background Coessentiality networks derived from CRISPR screens in cell lines provide a
powerful framework for identifying functional modules in the cell and for inferring the roles of …

Motivation The analysis of spatially resolved transcriptome enables the understanding of the
spatial interactions between the cellular environment and transcriptional regulation. In …

As a multifaceted syndrome, sepsis leads to high risk of death worldwide. It is difficult to be
intervened due to insufficient biomarkers and potential targets. The reason is that regulatory …

Recently, the intrauterine sterile environment theory has been questioned. Growing
evidence shows that microbial in utero pioneer gut colonization could occur prebirth, and …