Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants

C Liu, D Zhou, R Nutalai, HME Duyvesteyn… - Cell Host & Microbe, 2022 - cell.com
Summary Alpha-B. 1.1. 7, Beta-B. 1.351, Gamma-P. 1, and Delta-B. 1.617. 2 variants of
SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the …

Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …

Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants

WR Strohl, Z Ku, Z An, SF Carroll, BA Keyt, LM Strohl - BioDrugs, 2022 - Springer
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …

[HTML][HTML] Development of colorimetric sensors based on gold nanoparticles for SARS-CoV-2 RdRp, E and S genes detection

CR Díaz, N Lafuente-Gómez, C Coutinho, D Pardo… - Talanta, 2022 - Elsevier
We present a fast, reliable and easy to scale-up colorimetric sensor based on gold
nanoparticles (AuNPs) to detect the sequences coding for the RdRp, E, and S proteins of …

Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

MS Morgan, K Yan, TT Le, RA Johnston, AA Amarilla… - Viruses, 2022 - mdpi.com
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for …

Therapeutic antibodies for COVID-19: is a new age of IgM, IgA and bispecific antibodies coming?

J Zhang, H Zhang, L Sun - MAbs, 2022 - Taylor & Francis
Early humoral immune responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are dominated by IgM and IgA antibodies, which greatly contribute to virus …

Healthcare innovations to address the challenges of the COVID-19 pandemic

M Akay, S Subramaniam, C Brennan… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
We have been faced with an unprecedented challenge in combating the COVID-19/SARS-
CoV2 outbreak that is threatening the fabric of our civilization, causing catastrophic human …

Widely targeted metabolomic profiling combined with transcriptome analysis provides new insights into amino acid biosynthesis in green and red pepper fruits

X Fei, H Hu, Y Luo, Q Shi, A Wei - Food Research International, 2022 - Elsevier
The type and content of amino acids in pepper are important indicators to reflect its
nutritional value, largely affecting the purchasing behavior of consumers. Understanding the …