Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …

Exposure to early life stress (ELS) increases the risk for developing psychopathology;
however, the mechanisms underlying this association are not clear. In this study we …

Objective The immediate impact of child maltreatment on health and developmental
trajectories over time is unknown. Longitudinal studies starting in the direct aftermath of …

Background Longitudinal studies are needed to clarify whether early adversities are
associated with advanced methylation age or if they actually accelerate methylation aging …

Background The biopsychological response patterns to digital stress have been sparsely
investigated so far. Important potential stressors in modern working environments due to …

Background: The situation in the world today, encompassing multiple armed conflicts,
notably in Ukraine, the Coronavirus pandemic and the effects of climate change, increases …

Intimate partner violence (IPV) exposure continues to be a pervasive problem for children.
Although the impact of IPV exposure on children's mental health has been well-documented …

Childhood maltreatment increases risk for mood disorders and is associated with earlier
onset—and more pernicious disease course following onset—of mood disorders. While the …

Background Childhood maltreatment (CM) has long-term consequences for dysregulation of
the immune system which is particularly pronounced when mental and physical health …