The extent to which neurogenesis occurs in adult primates remains controversial. In this
study, using an optimized single-cell RNA sequencing pipeline, we profiled 207,785 cells …

Neurogenesis is significantly reduced in Alzheimer's disease (AD) and is a potential
therapeutic target. Contrary to humans, a zebrafish can regenerate its diseased brain, and …

Adult neural stem cells (aNSCs) are the source for the continuous production of new
neurons throughout life. This so-called adult neurogenesis has been extensively studied; the …

Stem cells in adult mammalian tissues are held in a reversible resting state, known as
quiescence, for prolonged periods of time. Recent studies have greatly increased our …

The skin of adult mammals protects from radiation, physical and chemical insults. While
melanocytes and melanocyte‐producing stem cells contribute to proper skin function in …

Telomerase reverse transcriptase (TERT) is expressed by quiescent adult stem cells (qASC)
in numerous adult murine and human tissues but has never been explored in the adult …

A telomerase reverse transcriptase (Tert) lineage-tracing mouse line was developed to
investigate the behavior and fate of adult tissue stem cells, by crossing the'Tet-On'system …

The skin of adult mammals protects from radiation, physical and chemical insults. While
melanocytes and melanocyte-producing stem cells contribute to proper skin function in …

Sonic Hedgehog (SHH) signaling has a critical role in mediating developmental
neurogenesis and has been implicated in adult subventricular (SVZ) neurogenesis …