Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride …
The underlying mechanisms for statin-induced myopathy (SIM) are still equivocal. In this
study, we employ Drosophila melanogaster to dissect possible underlying mechanisms for …
study, we employ Drosophila melanogaster to dissect possible underlying mechanisms for …
The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
AM Alsehli, S Liao, MH Al-Sabri, L Vasionis, A Purohit… - Pharmaceuticals, 2022 - mdpi.com
Statins, HMG Coenzyme A Reductase (HMGCR) inhibitors, are a first-line therapy, used to
reduce hypercholesterolemia and the risk for cardiovascular events. While sleep …
reduce hypercholesterolemia and the risk for cardiovascular events. While sleep …
Cardiac decompensation and promiscuous prenylation of small GTPases in cardiomyocytes in response to local mevalonate pathway disruption†
K Essandoh, RJ Auchus, MJ Brody - The Journal of pathology, 2022 - Wiley Online Library
Investigations of major mevalonate pathway enzymes have demonstrated the importance of
local isoprenoid synthesis in cardiac homeostasis. Farnesyl diphosphate synthase (FPPS) …
local isoprenoid synthesis in cardiac homeostasis. Farnesyl diphosphate synthase (FPPS) …
Analyzing Dynamically Expressed Proteins within the Heart
T Aye - 2022 - cdr.lib.unc.edu
Congenital heart disease (CHD) is one of the most prevalent forms of birth defects caused
by various abnormalities during embryonic development. To understand CHD, it is critical to …
by various abnormalities during embryonic development. To understand CHD, it is critical to …