Post-stroke cognitive impairment and dementia

NS Rost, A Brodtmann, MP Pase, SJ van Veluw… - Circulation …, 2022 - Am Heart Assoc
Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

Atrial fibrillation and dementia: a report from the AF-SCREEN international collaboration

L Rivard, L Friberg, D Conen, JS Healey, T Berge… - Circulation, 2022 - Am Heart Assoc
Growing evidence suggests a consistent association between atrial fibrillation (AF) and
cognitive impairment and dementia that is independent of clinical stroke. This report from the …

The role of inflammasomes in vascular cognitive impairment

L Poh, WL Sim, DG Jo, QN Dinh, GR Drummond… - Molecular …, 2022 - Springer
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …

New insights into cerebrovascular pathophysiology and hypertension

AJS Webb, DJ Werring - Stroke, 2022 - Am Heart Assoc
Despite advances in acute management and prevention of cerebrovascular disease, stroke
and vascular cognitive impairment together remain the world's leading cause of death and …

Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals

YH Koh, LZW Lew, KB Franke, AD Elliott, DH Lau… - EP …, 2022 - academic.oup.com
Aims To systematic review and meta-analyse the association and mechanistic links between
atrial fibrillation (AF) and cognitive impairment. Methods and results PubMed, EMBASE, and …

Framework for clinical trials in cerebral small vessel disease (FINESSE): a review

HS Markus, WM van Der Flier, EE Smith, P Bath… - JAMA …, 2022 - jamanetwork.com
Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most
common pathology underlying vascular cognitive impairment and dementia. An important …

Association of data-driven white matter hyperintensity spatial signatures with distinct cerebral small vessel disease etiologies

CL Phuah, Y Chen, JF Strain, N Yechoor… - Neurology, 2022 - AAN Enterprises
Background and Objectives Topographical distribution of white matter hyperintensities
(WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased …

Association of MRI indices of glymphatic system with amyloid deposition and cognition in mild cognitive impairment and Alzheimer disease

K Kamagata, C Andica, K Takabayashi, Y Saito… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

Multimodal biological brain age prediction using magnetic resonance imaging and angiography with the identification of predictive regions

P Mouches, M Wilms, D Rajashekar… - Human brain …, 2022 - Wiley Online Library
Biological brain age predicted using machine learning models based on high‐resolution
imaging data has been suggested as a potential biomarker for neurological and …

Cerebral small vessel disease and depression among intracerebral hemorrhage survivors

JP Castello, M Pasi, P Kubiszewski, JR Abramson… - Stroke, 2022 - Am Heart Assoc
Background and Purpose: Intracerebral hemorrhage (ICH) is an acute manifestation of
cerebral small vessel disease (CSVD), usually cerebral amyloid angiopathy or hypertensive …