[HTML][HTML] Ursolic acid: A natural modulator of signaling networks in different cancers

S Zafar, K Khan, A Hafeez, M Irfan, M Armaghan… - Cancer Cell …, 2022 - Springer
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the
development of resistance against currently available treatment strategies has contributed to …

[HTML][HTML] Ursolic acid analogs as potential therapeutics for cancer

SS Panda, M Thangaraju, BL Lokeshwar - Molecules, 2022 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits
and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The …

Oleanolic acid-conjugated human serum albumin nanoparticles encapsulating doxorubicin as synergistic combination chemotherapy in oropharyngeal carcinoma and …

S Kumbham, M Paul, A Itoo, B Ghosh… - International journal of …, 2022 - Elsevier
Combination chemotherapy produces a superior therapeutic response than monotherapy in
cancer. Human serum albumin and a naturally occurring cancer prophylactic/anticancer …

Recent advances in medicinal chemistry of oleanolic acid derivatives

YH Yang, SY Dai, FH Deng, LH Peng, C Li, YH Pei - Phytochemistry, 2022 - Elsevier
Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …

Advances in anti-inflammatory activity, mechanism and therapeutic application of ursolic acid

M Luan, H Wang, J Wang, X Zhang… - Mini Reviews in …, 2022 - ingentaconnect.com
In vivo and in vitro studies reveal that Ursolic Acid (UA) is able to counteract endogenous
and exogenous inflammatory stimuli and has favorable anti-inflammatory effects. The …

Applications of medicinal chemistry for drug discovery against Acanthamoeba infections

U Ahmed, A Anwar, SK Ong, A Anwar… - Medicinal research …, 2022 - Wiley Online Library
Acanthamoeba is a genus of free‐living amoebae, pervasively found in the environment.
Most of its pathogenic species are the causative agent of sight‐threatening Acanthamoeba …

Enhanced coverage and sensitivity of imprint DESI mass spectrometry imaging for plant leaf metabolites by post-photoionization

L Wu, K Qi, C Liu, Y Hu, M Xu, Y Pan - Analytical Chemistry, 2022 - ACS Publications
Plant metabolites exhibit a variety of different chemical properties, physiological activities,
and biological functions. However, untargeted imaging of highly diverse metabolic profiles is …

[HTML][HTML] Licorice (Glycyrrhiza glabra L.)-derived phytochemicals target multiple signaling pathways to confer oncopreventive and oncotherapeutic effects

HS Tuli, VK Garg, JK Mehta, G Kaur… - OncoTargets and …, 2022 - ncbi.nlm.nih.gov
Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over
the past few decades. Although chemotherapeutics and surgery are widely used in clinical …

[HTML][HTML] Anti-inflammatory medicinal plants of Bangladesh—a pharmacological evaluation

MA Akhtar - Frontiers in pharmacology, 2022 - frontiersin.org
Inflammatory diseases are considered major threats to human health worldwide. In
Bangladesh, a number of medicinal plants have been used in traditional medicine from time …

[HTML][HTML] Evidence of the beneficial effects of ursolic acid against lung cancer

A Kornel, M Nadile, E Tsiani - Molecules, 2022 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths globally. Despite current
treatment approaches that include surgery, chemotherapy, radiation and immunotherapies …