The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Alkyl organophosphate flame retardants (OPFRs), tri-n-butyl phosphate (TnBP) and tris (2-
butoxyethyl) phosphate (TBOEP), are ubiquitously detected in indoor and outdoor …

The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor that is well-known
for regulating xenobiotic metabolism. Studies in knockout and transgenic mice indicate that …

Nearly a quarter of the total number of deaths in the world are caused by unhealthy living or
working environments. Therefore, we consider it significant to introduce the effect of a widely …

Rationale Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, has been
considered as an important regulator for immune diseases. We have previously shown that …

Wnt5a is a key mediator of non-canonical Wnt signaling, and an early indicator of epithelial
injury and lung dysfunction. Polycyclic aromatic hydrocarbons (PAHs) could induce acute …

Ingestion of amino acids is fundamental for cellular activity. Amino acids are important
components for protein synthesis but are also crucial for intracellular metabolic reactions …

Abstract Objects Benzo (a) pyrene (BaP), an environmental pollutant, is present in high
concentrations in urban smog and cigarette smoke and has been reported to promote high …

Rationale: Th2 polarization plays a central role in the pathogenesis of allergic diseases such
as airway allergy. The underlying mechanism is not fully understood yet. X-box-binding …