The lactoferrin phenomenon—a miracle molecule

P Kowalczyk, K Kaczyńska, P Kleczkowska… - Molecules, 2022 - mdpi.com
Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

Clinical implications of preterm infant gut microbiome development

DB Healy, CA Ryan, RP Ross, C Stanton… - Nature …, 2022 - nature.com
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

Perinatal origins of adult disease and opportunities for health promotion: a narrative review

S Nobile, C Di Sipio Morgia, G Vento - Journal of Personalized Medicine, 2022 - mdpi.com
The “developmental origins of health and disease”(DOHaD) hypothesis refers to the
influence of early developmental exposures and fetal growth on the risk of chronic diseases …

Lactoferrin for iron-deficiency anemia in children with inflammatory bowel disease: a clinical trial

D El Amrousy, D El-Afify, A Elsawy, M Elsheikh… - Pediatric …, 2022 - nature.com
Background Iron-deficiency anemia (IDA) is common in children with inflammatory bowel
disease (IBD); however, oral iron supplements are commonly associated with poor …

The application of lactoferrin in infant formula: The past, present and future

W Li, B Liu, Y Lin, P Xue, Y Lu, S Song… - Critical Reviews in …, 2022 - Taylor & Francis
Human milk is universally regarded as the gold standard to fulfill nutrition needs of infants.
Lactoferrin (LF) is a major multiple bioactive glycoprotein in human milk but little is …

Neonatal invasive candidiasis: updates on clinical management and prevention

R Kilpatrick, E Scarrow, C Hornik… - The Lancet Child & …, 2022 - thelancet.com
Neonatal invasive candidiasis is an important cause of morbidity and mortality in preterm
infants. The incidence of invasive candidiasis in this population has been declining in high …

Effects of antioxidants in human milk on bronchopulmonary dysplasia prevention and treatment: A review

X Yang, S Jiang, X Deng, Z Luo, A Chen, R Yu - Frontiers in nutrition, 2022 - frontiersin.org
Bronchopulmonary dysplasia (BPD) is a severe chronic lung illness that affects neonates,
particularly premature infants. It has far-reaching consequences for infant health and their …

Oral lactoferrin supplementation during induction chemotherapy promotes gut microbiome eubiosis in pediatric patients with hematologic malignancies

F D'Amico, N Decembrino, E Muratore, S Turroni… - Pharmaceutics, 2022 - mdpi.com
Induction chemotherapy is the first-line treatment for pediatric patients with hematologic
malignancies. However, several complications may arise, mainly infections and febrile …

Knowledge gaps in late-onset neonatal sepsis in preterm neonates: a roadmap for future research

S Kurul, K Fiebig, RB Flint, IKM Reiss, H Küster… - Pediatric …, 2022 - nature.com
Late-onset neonatal sepsis (LONS) remains an important threat to the health of preterm
neonates in the neonatal intensive care unit. Strategies to optimize care for preterm …

[HTML][HTML] Immunological effects of adding bovine lactoferrin and reducing iron in infant formula: a randomized controlled trial

M Björmsjö, O Hernell, B Lönnerdal… - Journal of Pediatric …, 2022 - journals.lww.com
Objectives: Compared to formula-fed infants, breastfed infants have a lower risk of infections.
Two possible reasons for this are the presence of the anti-infective and anti-inflammatory …