Importance Appendectomy remains the standard of care for uncomplicated acute
appendicitis despite several randomized clinical trials pointing to the safety and efficacy of …

Background This aim of this study was to provide an updated meta-analysis comparing
antibiotic therapy with appendicectomy in adults (16 years or older) with uncomplicated …

There is a clear need for simple resources to improve the quality of antibiotic prescribing
globally. The AWaRe book was designed as a tool to make the antibiotics section of the …

Appendicitis is one of the most common surgical emergencies in children and adults.
Appendectomy as the standard care has been challenged in the recent years with growing …

Importance Use of antibiotics for the treatment of appendicitis is safe and has been found to
be noninferior to appendectomy based on self-reported health status at 30 days. Identifying …

Background Non-operative management of uncomplicated acute appendicitis is an option,
but omission of antibiotics from the regimen has not been tested. Methods A double-blind …

(1) Background: How to best define, diagnose and differentiate uncomplicated from
complicated acute appendicitis remains debated. Hence, the aim of this review was to …

Acute appendicitis is a common abdominal surgical emergency worldwide. Abraham Groves
performed the first documented open appendectomy in 1883. Although appendectomy is still …

Background Non‐operative management (NOM) of uncomplicated acute appendicitis (AA)
has been introduced as an alternative to appendectomy. This umbrella review aimed to …

BACKGROUND AND OBJECTIVES Several studies have revealed the success of
nonoperative management (NOM) of uncomplicated appendicitis in children. Large studies …