Adolescence is characterized by the maturation of cortical microstructure and connectivity supporting complex cognition and behavior. Axonal myelination influences brain …
The brain is organized into networks at multiple resolutions, or scales, yet studies of functional network development typically focus on a single scale. Here, we derive …
The functions of the human brain are metabolically expensive and reliant on coupling between cerebral blood flow (CBF) and neural activity, yet how this coupling evolves over …
Neurodevelopmental theories suggest goal-directed cognitive abilities (executive functions) mature from childhood through adolescence, and deviations from their normative …
Inhibitory control can be less reliable in adolescence, however, in the presence of rewards, adolescents' performance often improves to adult levels. Dopamine is known to play a role …
ME Fields, AE Mirro, MM Binkley… - American journal of …, 2022 - Wiley Online Library
Patients with sickle cell anemia (SCA) experience cerebral metabolic stress with an increase in oxygen extraction fraction (OEF) to compensate for reduced oxygen carrying capacity due …
Adolescence is defined by puberty and represents a period characterized by neural circuitry maturation (eg, fronto-striatal systems) facilitating cognitive improvements. Though studies …
Dopamine-related abnormalities in the basal ganglia have been implicated in attention- deficit/hyperactivity disorder (ADHD). Iron plays a critical role in supporting dopaminergic …
D Nakhid, C McMorris, H Sun… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Prenatal alcohol exposure (PAE) can negatively affect brain development thereby increasing the risk of cognitive deficits, behavioral challenges, and mental health …