A multi‐hit hypothesis for an APOE4‐dependent pathophysiological state
The APOE gene encoding the Apolipoprotein E protein is the single most significant genetic
risk factor for late‐onset Alzheimer's disease. The APOE4 genotype confers a significantly …
risk factor for late‐onset Alzheimer's disease. The APOE4 genotype confers a significantly …
Induction of Endoplasmic Reticulum Stress by CdhM Mediates Apoptosis of Macrophage During Mycobacterium tuberculosis Infection
P Xu, J Tang, ZG He - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
The normal operation of the endoplasmic reticulum (ER) is critical for cells and organisms.
However, ER stress, caused by imbalanced protein folding, occurs frequently, which …
However, ER stress, caused by imbalanced protein folding, occurs frequently, which …
Protective role of hepassocin against hepatic endoplasmic reticulum stress in mice
Y Yang, H Chen, Y Wan, D Dong, X Wang… - International Journal of …, 2022 - mdpi.com
Hepassocin (HPS) is a hepatokine that has multiple proposed physiological functions. Some
of the biological processes in which it is involved are closely related to endoplasmic …
of the biological processes in which it is involved are closely related to endoplasmic …
Transcriptomic and epigenetic assessment of ageing female skin and fibroblasts identifies age related reduced oxidative phosphorylation is exacerbated by smoking
LI Pease, J Wordsworth, D Shanley - bioRxiv, 2022 - biorxiv.org
Skin ageing has been widely associated with the formation and presence of increasing
quantities of senescent cells, the presence of which are thought to reduce cell renewal. This …
quantities of senescent cells, the presence of which are thought to reduce cell renewal. This …
Transcriptomic and epigenetic assessment of ageing male skin identifies disruption of Ca2+ homeostasis; exacerbated by smoking and UV exposure
LI Pease, J Wordsworth, D Shanley - bioRxiv, 2022 - biorxiv.org
Skin ageing has been widely associated with the formation and presence of increasing
quantities of senescent cells, the presence of which are thought to reduce cell renewal. This …
quantities of senescent cells, the presence of which are thought to reduce cell renewal. This …
[PDF][PDF] Aging is selected for, adaptive, and programmed. 31. Is there a fountain of youth?
K Heininger - researchgate.net
The therapeutic strategies targeting the hallmarks of aging have been broadly grouped into
four categories, namely systemic (blood) factors, metabolic manipulation (diet regimens and …
four categories, namely systemic (blood) factors, metabolic manipulation (diet regimens and …
Correction: Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress
M Torres, K Castillo, R Armisén, A Stutzin, C Soto… - Plos one, 2022 - journals.plos.org
An error was made in preparing the Actin panel of Fig 3A of this article [1]: lanes 1, 11, and
12 from the original blot should not have been included. An updated Fig 3 is provided here …
12 from the original blot should not have been included. An updated Fig 3 is provided here …