The humoral response and antibodies against SARS-CoV-2 infection
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …
Antibodies to combat viral infections: development strategies and progress
G Pantaleo, B Correia, C Fenwick, VS Joo… - Nature Reviews Drug …, 2022 - nature.com
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …
viral infections owing to characteristics such as their high specificity and their ability to …
Antibody escape of SARS-CoV-2 Omicron BA. 4 and BA. 5 from vaccine and BA. 1 serum
A Tuekprakhon, R Nutalai, A Dijokaite-Guraliuc… - Cell, 2022 - cell.com
The Omicron lineage of SARS-CoV-2, which was first described in November 2021, spread
rapidly to become globally dominant and has split into a number of sublineages. BA. 1 …
rapidly to become globally dominant and has split into a number of sublineages. BA. 1 …
[HTML][HTML] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B. 1.1.
529 was announced, containing far more mutations in Spike (S) than previously reported …
529 was announced, containing far more mutations in Spike (S) than previously reported …
Potent cross-reactive antibodies following Omicron breakthrough in vaccinees
Highly transmissible Omicron variants of SARS-CoV-2 currently dominate globally. Here, we
compare neutralization of Omicron BA. 1, BA. 1.1, and BA. 2. BA. 2 RBD has slightly higher …
compare neutralization of Omicron BA. 1, BA. 1.1, and BA. 2. BA. 2 RBD has slightly higher …
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models
HY Huang, HY Liao, X Chen, SW Wang… - Science Translational …, 2022 - science.org
A major challenge to end the pandemic caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term …
coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term …
Structural and antigenic variations in the spike protein of emerging SARS-CoV-2 variants
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus is continuously
evolving, and this poses a major threat to antibody therapies and currently authorized …
evolving, and this poses a major threat to antibody therapies and currently authorized …
In-cell structural biology by NMR: the benefits of the atomic scale
FX Theillet - Chemical reviews, 2022 - ACS Publications
In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …
acids in their native, cellular environment. This emerging field holds great promise and is …
[HTML][HTML] A structural view of the SARS-CoV-2 virus and its assembly
NJ Hardenbrook, P Zhang - Current opinion in virology, 2022 - Elsevier
Highlights•Structural biology plays a vital role in SARS-CoV-2 vaccine and treatment.•High-
resolution structures of SARS-CoV-2 proteins and complexes have been obtained.•In situ …
resolution structures of SARS-CoV-2 proteins and complexes have been obtained.•In situ …
The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants
Summary Alpha-B. 1.1. 7, Beta-B. 1.351, Gamma-P. 1, and Delta-B. 1.617. 2 variants of
SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the …
SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the …