Advances in the research of the role of macrophage/microglia polarization-mediated inflammatory response in spinal cord injury

SP Fu, SY Chen, QM Pang, M Zhang, XC Wu… - Frontiers in …, 2022 - frontiersin.org
It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

The importance of the IL‐1 family of cytokines in nanoimmunosafety and nanotoxicology

G Zhang, W Luo, W Yang, S Li, D Li… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Engineered nanomaterials (ENMs) to which humans are exposed intentionally as
nanomedicines or unintentionally as invaders, may elicit unforeseen immune reactions. An …

Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury

L Wen, YD Wang, DF Shen, PD Zheng… - Neural regeneration …, 2022 - journals.lww.com
Exosomes derived from bone marrow mesenchymal stem cells can inhibit
neuroinflammation through regulating microglial phenotypes and promoting nerve injury …

Distinct non‐coding RNA cargo of extracellular vesicles from M1 and M2 human primary macrophages

P Pantazi, T Clements, M Venø… - Journal of …, 2022 - Wiley Online Library
Macrophages are important antigen presenting cells which can release extracellular
vesicles (EVs) carrying functional cargo including non‐coding RNAs. Macrophages can be …

PCSK9 confers inflammatory properties to extracellular vesicles released by vascular smooth muscle cells

MF Greco, AS Rizzuto, M Zarà, M Cafora… - International journal of …, 2022 - mdpi.com
Vascular smooth muscle cells (VSMCs) are key participants in both early-and late-stage
atherosclerosis and influence neighbouring cells possibly by means of bioactive molecules …

Synovial fluid in knee osteoarthritis extends proinflammatory niche for macrophage polarization

P Kulkarni, V Srivastava, K Tootsi, A Electricwala… - Cells, 2022 - mdpi.com
Macrophage polarization is a steering factor of osteoarthritis (OA) progression. Synovial fluid
(SF) obtained from OA patients with different Kellgren–Lawrence grades (KL grades) holds …

Safety and the probiotic potential of Bifidobacterium animalis CP‐9

HY Tsai, YC Wang, CA Liao, CY Su… - Journal of Food …, 2022 - Wiley Online Library
Bifidobacterium animalis CP‐9 was a commensal strain isolated from human breast milk. In
this study, genetic and 90‐day oral toxicity were assessed in rodents for its safety. Ames test …

Shionone Attenuates Sepsis-Induced Acute Kidney Injury by Regulating Macrophage Polarization via the ECM1/STAT5 Pathway

B Zhang, Y Xue, J Zhao, H Jiang, J Zhu, H Yin… - Frontiers in …, 2022 - frontiersin.org
Backgrounds To date, there are no specific drugs approved for the treatment of sepsis
associated acute kidney injury (AKI). Shionone is a natural component with anti …

[HTML][HTML] Поляризация макрофагов: механизмы, маркеры и факторы индукции

АА Федоров, НА Ермак, ТС Геращенко… - Сибирский …, 2022 - cyberleninka.ru
Макрофаги являются ключевыми компонентами врожденной иммунной системы.
Вариативность участия макрофагов в различных патологических процессах …

G6PD is a critical enabler of hypoxia-induced accumulation of macrophages and platelets in mice lungs and contributor to lung inflammation

R Hashimoto, SA Gupte - Vascular Pharmacology, 2022 - Elsevier
Metabolic reprogramming-driven inflammation is emerging as central processes in the
pathogenesis of pulmonary hypertension (PH). Although extensive work is ongoing to …