Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response

X Xie, J Gu, D Zhuang, Y Zhou, X Chen… - Journal of Clinical …, 2022 - Wiley Online Library
Objective Genetic variations can affect individual response to methadone maintenance
treatment (MMT) for heroin addiction. The A118G variant (rs1799971) in the mu opioid …

Pharmacogenetics of addiction therapy

DP Graham, MJ Harding, DA Nielsen - Pharmacogenomics in Drug …, 2022 - Springer
Drug addiction is a serious relapsing disease that has high costs to society and to the
individual addicts. Treatment of these addictions is still in its nascency, with only a few …

Association of the D-amino acid oxidase gene with methadone dose in heroin dependent patients under methadone maintenance treatment

TH Liu, HH Tsou, RH Chung, SC Liu… - Journal of Human …, 2022 - nature.com
Methadone is a synthetic opioid used for the maintenance treatment (MMT) of heroin
dependence. It primarily binds to the μ-opioid receptor (MOR; with its gene, namely …

A study on methylation of two CpG islands of MAOA gene promoter among opium-addicted males undergoing methadone treatment

V Omarmeli, A Sharafshah, A Albonaim… - … Nucleotides & Nucleic …, 2022 - Taylor & Francis
The association between methylation of MAOA gene promoter and alcohol and nicotine
dependence has been demonstrated in women but not in men yet. Antisocial personality …

[PDF][PDF] Nghiên cứu đa hình đơn gen OPRM1 và ABCD1 ở bệnh nhân nghiện chất dạng thuốc phiện điều trị methadone thay thế

VC Trần, KC Trần, TND Đặng, TPD Trịnh, QG Nguyễn… - 2022 - thuvienlamdong.org.vn
Trong nghiên cứu dược lý di truyền học, biểu hiện của các đa hình đơn (Single nucleotide
polymorphism–SNP) khác nhau có thể làm thay đổi đáp ứng với thuốc. Mục tiêu nghiên cứu …