Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs

D Terentes-Printzios, N Ioakeimidis, K Rokkas… - Nature Reviews …, 2022 - nature.com
Sexual health has a fundamental role in overall health and well-being, and a healthy and
dynamic sex life can make an important contribution to a good quality of life. Sexual …

The roles of androgens in humans: biology, metabolic regulation and health

M Alemany - International journal of molecular sciences, 2022 - mdpi.com
Androgens are an important and diverse group of steroid hormone molecular species. They
play varied functional roles, such as the control of metabolic energy fate and partition, the …

Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis

J Hudson, M Cruickshank, R Quinton… - The Lancet Healthy …, 2022 - thelancet.com
Background Testosterone is the standard treatment for male hypogonadism, but there is
uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide …

Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism

CN Jayasena, RA Anderson, S Llahana… - Clinical …, 2022 - Wiley Online Library
Male hypogonadism (MH) is a common endocrine disorder. However, uncertainties and
variations in its diagnosis and management exist. There are several current guidelines on …

Adult-and late-onset male hypogonadism: the clinical practice guidelines of the Italian Society of Andrology and Sexual Medicine (SIAMS) and the Italian Society of …

AM Isidori, A Aversa, A Calogero, A Ferlin… - Journal of …, 2022 - Springer
Purpose To provide the evidence-based recommendations on the role of testosterone (T) on
age-related symptoms and signs remains. Methods The Italian Society of Andrology and …

The role of testosterone in the elderly: what do we know?

B Barone, L Napolitano, M Abate, L Cirillo… - International journal of …, 2022 - mdpi.com
Testosterone is the most important hormone in male health. Aging is characterized by
testosterone deficiency due to decreasing testosterone levels associated with low testicular …

Importance of sex and gender in ischaemic stroke and carotid atherosclerotic disease

K Gasbarrino, D Di Iorio… - European Heart …, 2022 - academic.oup.com
Stroke is a leading cause of death and disability worldwide. Women are disproportionately
affected by stroke, exhibiting higher mortality and disability rates post-stroke than men …

Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy

Y Pan, PB Davis, DC Kaebler, RP Blankfield… - Cardiovascular …, 2022 - Springer
Background Gabapentin and pregabalin are commonly prescribed medications to treat pain
in patients with diabetic neuropathy. Gabapentin and pregabalin can cause fluid retention …

Senolytic treatment rescues blunted muscle hypertrophy in old mice

CM Dungan, VC Figueiredo, Y Wen, GL VonLehmden… - Geroscience, 2022 - Springer
With aging, skeletal muscle plasticity is attenuated in response to exercise. Here, we report
that senescent cells, identified using senescence-associated β-galactosidase (SA β-Gal) …

Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology

N Narinx, K David, J Walravens, P Vermeersch… - Cellular and Molecular …, 2022 - Springer
According to the free hormone hypothesis, biological activity of a certain hormone is best
reflected by free rather than total hormone concentrations. A crucial element in this theory is …