In silico evaluation of binding of 2-deoxy-D-glucose with Mpro of nCoV to combat COVID-19
COVID-19 has threatened the existence of humanity andthis infection occurs due to SARS-
CoV-2 or novel coronavirus, was first reported in Wuhan, China. Therefore, there is a need …
CoV-2 or novel coronavirus, was first reported in Wuhan, China. Therefore, there is a need …
Crystal structure, Hirshfeld, computational biomolecular investigations, and MTT assay studies of amino pyrimidine derivative as EGFR kinase domain inhibitor
A nitrogen heterocyclic pyrimidine fused heterocyclic derivative 4-(4-Methoxyphenyl)-6-(2-
phenylethyl) pyrimidin-2-amine (MPPPA), was synthesized and crystal structure is identified …
phenylethyl) pyrimidin-2-amine (MPPPA), was synthesized and crystal structure is identified …
Comparison of herbicide specificity of CYP81A cytochrome P450s from rice and a multiple‐herbicide resistant weed, Echinochloa phyllopogon
W Ha, T Yamaguchi, S Iwakami… - Pest Management …, 2022 - Wiley Online Library
Abstract BACKGROUND CYP81A cytochrome P450s (CYP81As) play a key role in
herbicide detoxification in Poaceae plants. Crop CYP81As confer natural tolerance to …
herbicide detoxification in Poaceae plants. Crop CYP81As confer natural tolerance to …
Metabolites profiling and molecular docking identification of putative leads from endophytic Phyllosticta capitalensis as modulators of key druggable structural targets …
T Garuba, R Govender, HA Isah… - Transactions of the Royal …, 2022 - journals.co.za
Rotavirus-induced gastroenteritis is a global health concern and the leading cause of death
in low-income countries and children under the age of five. While rotavirus A (RVA) vaccines …
in low-income countries and children under the age of five. While rotavirus A (RVA) vaccines …
Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes
CS Bodourian, N Poudel, AC Papageorgiou… - International Journal of …, 2022 - mdpi.com
Glutathione transferases (GSTs; EC 2.5. 1.18) form a group of multifunctional enzymes that
are involved in phase II of the cellular detoxification mechanism and are associated with …
are involved in phase II of the cellular detoxification mechanism and are associated with …
Sodium Malonate Inhibits the AcrAB-TolC Multidrug Efflux Pump of Escherichia coli and Increases Antibiotic Efficacy
A Cauilan, C Ruiz - Pathogens, 2022 - mdpi.com
There is an urgent need to find novel treatments for combating multidrug-resistant bacteria.
Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this …
Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this …
[PDF][PDF] A Comparative Study for the Accuracy of Three Molecular Docking Programs Using HIV-1 Protease Inhibitors as a Model
TM Salih - Iraqi Journal of Pharmaceutical Sciences (P-ISSN 1683 …, 2022 - iasj.net
Flexible molecular docking is a computational method of structure-based drug design. This
method is used to evaluate binding interactions between receptor and ligand and identify …
method is used to evaluate binding interactions between receptor and ligand and identify …
[HTML][HTML] The role of eugenol and ferulic acid as the competitive inhibitors of transcriptional regulator RhlR in P. aeruginosa
E Escobar-Muciño - MethodsX, 2022 - Elsevier
Abstract Search inhibitors of Quorum Sensing (QS) in Pseudomonas aeruginosa are
challenging to find therapies due to the broad antibiotic resistance. Therefore, this study …
challenging to find therapies due to the broad antibiotic resistance. Therefore, this study …
A computational design of siRNA in SARS-CoV-2 spike glycoprotein gene and its binding capability toward mRNA
AA Parikesit, ANM Ansori… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
COVID-19 pandemic has no immediate ending in sight, and any significant increasing cases
were observed worldwide. Currently, there are only two main strategies for developing …
were observed worldwide. Currently, there are only two main strategies for developing …
[HTML][HTML] Designing a bis-azide photoaffinity probe in labeling influenza nucleoprotein trimer to give an insight into the binding mode
PH Chiu, W Huang, HT Hsu, WF Huang, YT Wu… - European Journal of …, 2022 - Elsevier
Targeting the highly conserved E330… R416 salt bridge involved in nucleoprotein (NP)
trimerization is considered a favorable approach to address the problem of drug resistance …
trimerization is considered a favorable approach to address the problem of drug resistance …