Functional diversity in the RAS subfamily of small GTPases

G Bernal Astrain, M Nikolova… - Biochemical Society …, 2022 - portlandpress.com
RAS small GTPases regulate important signalling pathways and are notorious drivers of
cancer development and progression. While most research to date has focused on …

Circ_0000190 sponges miR-382-5p to suppress cell proliferation and motility and promote cell death by targeting ZNRF3 in gastric cancer

M Jiang, R Mo, C Liu, H Wu - The Journal of Biochemistry, 2022 - academic.oup.com
This study was to explore the role of circRNA_0000190 (circ_0000190) in gastric cancer
(GC) progression. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) …

Circ_0022340 promotes colorectal cancer progression via HNRNPC/EBF1/SYT7 or miR-382-5p/ELK1 axis

Z Liu, X Xu, D Chen, L Zhang, Y Pan, D Liu… - Cellular and Molecular …, 2022 - cellmolbiol.org
Circular RNAs (circRNAs) are characterized as a class of new noncoding RNAs and function
in tumorigenesis of colorectal cancer (CRC). In our study, the molecule mechanism of …

MiR-382 Functions on the Regulation of Melanogenesis via Targeting dct in Rainbow Trout (Oncorhynchus mykiss)

S Wu, J Huang, Y Li, Z Liu, L Zhao - Marine Biotechnology, 2022 - Springer
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that are involved in
a diverse collection of biological processes as important post-transcriptional regulators …

Structural analysis of random transgene integration in CHO manufacturing cell lines by targeted sequencing

A Stadermann, M Gamer, J Fieder… - Biotechnology and …, 2022 - Wiley Online Library
Genetically modified CHO cell lines are traditionally used for the production of
biopharmaceuticals. However, an in‐depth molecular understanding of the mechanism and …

MicroRNA-382-5p Promotes Oral Squamous Cell Carcinoma Development and Progression by Negatively Regulating PTEN Expression

X Xu, B Jin, L Cai, Z Zhang, Y Ying, J Luo - Journal of Oral and Maxillofacial …, 2022 - Elsevier
Purpose Oral squamous cell carcinoma (OSCC) local recurrence and distant metastasis
remain a poorly understood clinical challenge. The objective of this study was to investigate …

Serum MicroRNAs:-28-3p,-31-5p,-378a-3p, and-382-5p as novel potential biomarkers in acute lymphoblastic leukemia

Z Derakhshan, G Khamisipour, FH Soleimani… - Gene Reports, 2022 - Elsevier
Introduction Acute lymphoblastic leukemia (ALL) is the most common malignancy in children
and accounts for 20% of acute leukemia in adults. Recently, microRNAs (miRNAs) have …

The NFAT3/RERG Complex in Luminal Breast Cancers Is Required to Inhibit Cell Invasion and May Be Correlated With an Absence of Axillary Lymph Nodes …

L Coillard, F Guaddachi, M Ralu, E Brabencova… - Frontiers in …, 2022 - frontiersin.org
Luminal breast cancers represent 70% of newly diagnosed breast cancers per annum and
have a relatively good prognosis compared with triple-negative breast cancers. Luminal …

Exploring Context-Specific Expression Variation and Distal Gene Regulation Via Latent Variable Models

ADH Gewirtz - 2022 - search.proquest.com
As genome-wide sequencing expands across diverse populations, we are approaching a
comprehensive understanding of the critical roles that genetic variation plays in gene …