[PDF][PDF] Hunter-gatherer genomes reveal diverse demographic trajectories during the rise of farming in Eastern Africa

S Gopalan, REW Berl, JW Myrick, ZH Garfield… - Current Biology, 2022 - cell.com
The fate of hunting and gathering populations following the rise of agriculture and
pastoralism remains a topic of debate in the study of human prehistory. Studies of ancient …

Demographic and selection histories of populations across the Sahel/Savannah belt

C Fortes-Lima, P Tříska, M Čížková… - Molecular biology …, 2022 - academic.oup.com
Abstract The Sahel/Savannah belt harbors diverse populations with different demographic
histories and different subsistence patterns. However, populations from this large African …

Signatures of convergent evolution and natural selection at the alcohol dehydrogenase gene region are correlated with agriculture in ethnically diverse Africans

MA McQuillan, A Ranciaro, MEB Hansen… - Molecular Biology …, 2022 - academic.oup.com
The alcohol dehydrogenase (ADH) family of genes encodes enzymes that catalyze the
metabolism of ethanol into acetaldehyde. Nucleotide variation in ADH genes can affect the …

Ancient human DNA and African population history

KA Sirak, EA Sawchuk, ME Prendergast - … Research Encyclopedia of …, 2022 - oxfordre.com
Ancient DNA has emerged as a powerful tool for investigating the human past and
reconstructing the movements, mixtures, and adaptations that have structured genetic …

[PDF][PDF] Ancient DNA studies and African population history

M Vicente, C Schlebusch - Africa, The Cradle of Human Diversity …, 2022 - library.oapen.org
In the last three decades, genetics played an increasingly important role in the inference of
human history. Genetic studies provided conclusive information that helped to answer …

Predicting environmental and ecological drivers of human population structure

E Pless, AM Eckburg, BM Henn - bioRxiv, 2022 - biorxiv.org
Landscape, climate, and culture can all structure human populations, but few methods are
designed to disentangle the importance of these many variables. We developed a machine …

Beta-cell dysfunction and insulin resistance in relation to abnormal glucose tolerance in African populations: can we afford to ignore the diversity within African …

KAC Meeks, A Adeyemo, C Agyemang - BMJ Open Diabetes Research …, 2022 - drc.bmj.com
The pathogenesis of type 2 diabetes (T2D) in sub-Saharan Africans is incompletely
understood despite the rapid increase in T2D prevalence in sub-Saharan Africa. T2D and its …