The immune checkpoint pathway consisting of the cell membrane-bound molecule
programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate …

Programmed cell death protein-1 (PD-1) is a checkpoint receptor expressed on the surface
of various immune cells. PD-L1, the natural receptor for PD-1, is mainly expressed in tumor …

Simple Summary The search for non-invasive biomarkers is a hot topic in modern oncology,
since a tissue biopsy has significant limitations in terms of cost and invasiveness. The …

Cancer is a gravely important health issue all over the world and has been spreading fast. In
recent years immune checkpoint treatment options have been used extensively as a primary …

Background Hepatocellular carcinoma (HCC) is currently a leading cause of cancer-related
death, and its prognostic evaluation remains a challenge. We aimed to explore the …

Background Our preclinical research reveals that radiotherapy (RT) promoted PD-L1
upregulation in tumor tissues and that higher PD-L1 after RT worsened the prognosis …

Background: Programmed death-ligand 1 (PD-L1) and programmed cell death protein 1 (PD-
1) have been reported as possibly favorable prognostic factors in colorectal cancer (CRC) …

The scale of the HBV epidemic and the burden of HBV-related disease is substantial, yet our
current understanding of the epidemiology, disease pathogenesis and immunological …

The treatment perspectives of advanced hepatocellular carcinoma (HCC) have deeply
changed after the introduction of immunotherapy. The results in responders show improved …

Background: Hepatocellular carcinoma (HCC) is the fifth most commonly occurring cancer
worldwide and the third cause of mortality due to cancer. Many clinical and laboratory …