The DNA double-strand break repair in glioma: Molecular players and therapeutic strategies
S Maksoud - Molecular Neurobiology, 2022 - Springer
Gliomas are the most frequent type of tumor in the central nervous system, which exhibit
properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and …
properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and …
Evaluation of proton-induced DNA damage in 3D-engineered glioblastoma microenvironments
Q Akolawala, M Rovituso, HH Versteeg… - … applied materials & …, 2022 - ACS Publications
Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis.
For this reason, besides clinical and preclinical studies, novel in vitro models for the …
For this reason, besides clinical and preclinical studies, novel in vitro models for the …
[HTML][HTML] NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells
M Douyère, C Gong, M Richard… - Cancer Cell …, 2022 - Springer
Background Medulloblastoma (MB) is the most common pediatric malignant brain tumor.
Despite current therapies, the morbidity and recurrent risk remains significant. Neuropilin-1 …
Despite current therapies, the morbidity and recurrent risk remains significant. Neuropilin-1 …
Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by 89Zr Immuno-PET
KH Jung, JH Lee, M Kim, EJ Lee, YS Cho… - Molecular …, 2022 - journals.sagepub.com
We developed an immuno-PET technique that monitors modulation of tumor CD133
expression, which is required for the success of CD133-targeted therapies. Methods. Anti …
expression, which is required for the success of CD133-targeted therapies. Methods. Anti …
Construction and evaluation of a prognostic risk assessment model of gastric cancer by using hypoxia features
X Zhu, J Wang, X Jin, Y Chen, L Hu, J Zhao - … Research/Fundamental and …, 2022 - Elsevier
In this study, mRNA expression of gastric cancer tissue and clinical data of patients in TCGA-
STAD dataset were used, together with the hypoxia-related gene sets in the MsigDB …
STAD dataset were used, together with the hypoxia-related gene sets in the MsigDB …
PNJ scaffolds promote microenvironmental regulation of glioblastoma stem-like cell enrichment and radioresistance
JM Heffernan, JB McNamara, BL Vernon… - Biomaterials …, 2022 - pubs.rsc.org
Glioblastoma (GBM) brain tumors contain a subpopulation of self-renewing multipotent
Glioblastoma stem-like cells (GSCs) that are believed to drive the near inevitable recurrence …
Glioblastoma stem-like cells (GSCs) that are believed to drive the near inevitable recurrence …
Regulation of iron metabolism in radioresistant glioblastoma
MY Ali - 2022 - search.proquest.com
Glioblastoma (GBM) is the most common and most lethal adult primary malignant brain
tumor. Median progression-free and overall survival after initial diagnosis are 6.2-7.5 and 14 …
tumor. Median progression-free and overall survival after initial diagnosis are 6.2-7.5 and 14 …
[HTML][HTML] Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb
C Degorre, IC Sutton, SL Lehman… - Cancer Cell …, 2022 - Springer
Background The invasive nature of GBM combined with the diversity of brain
microenvironments creates the potential for a topographic heterogeneity in GBM …
microenvironments creates the potential for a topographic heterogeneity in GBM …