Novel therapies in axial spondyloarthritis
M Bittar, P Mease - Best Practice & Research Clinical Rheumatology, 2022 - Elsevier
Over the past two decades, advancements in understanding the pathogenesis of axial
spondyloarthritis have led to discoveries of new therapeutic targets, particularly the …
spondyloarthritis have led to discoveries of new therapeutic targets, particularly the …
The MK2 cascade mediates transient alteration in mGluR‐LTD and spatial learning in a murine model of Alzheimer's disease
L Privitera, EL Hogg, M Lopes, LB Domingos… - Aging cell, 2022 - Wiley Online Library
A key aim of Alzheimer disease research is to develop efficient therapies to prevent and/or
delay the irreversible progression of cognitive impairments. Early deficits in long‐term …
delay the irreversible progression of cognitive impairments. Early deficits in long‐term …
Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer
D Morgan, KL Berggren, CD Spiess… - Molecular …, 2022 - Wiley Online Library
Cancer and the immune system share an intimate relationship. Chronic inflammation
increases the risk of cancer occurrence and can also drive inflammatory mediators into the …
increases the risk of cancer occurrence and can also drive inflammatory mediators into the …
Excessive hydrogen sulfide causes lung and brain tissue damage by promoting PARP1/Bax and C9 and inhibiting LAMB1
R Luo, T Wang, S Zhuo, X Guo, D Ma - Apoptosis, 2022 - Springer
Excessive hydrogen sulfide (H2S) causes serious damage to human organs and tissues. In
this study, we aimed to explore the role and underlying mechanism of excessive H2S in …
this study, we aimed to explore the role and underlying mechanism of excessive H2S in …