Epilepsy, one of the most severe neurological diseases, is characterized by abrupt recurrent
seizures. Despite great progress in the development of antiseizure drugs (ASDs) based on …

Epilepsy is considered a circuit-level dysfunction associated with imbalanced excitation-
inhibition, it is therapeutically necessary to identify key brain regions and related circuits in …

Epilepsy is a common neurological disorder characterized by hyperexcitability in the brain.
Its pathogenesis is classically associated with an imbalance of excitatory and inhibitory …

Temporal lobe epilepsy (TLE) is a common kind of refractory epilepsy. More than 30% TLE
patients were multi-drug resistant. Some patients may even develop into status epilepticus …

Low frequency deep brain electrical stimulation (LFS) is a potential therapeutic strategy to
control seizures in epilepsy patients. Given the functional connection of the olfactory bulb …

Cognitive deficit is a common comorbidity in temporal lobe epilepsy (TLE) and is not well
controlled by current therapeutics. Currently, how epileptic seizure affects cognitive …