The T cell immune response against SARS-CoV-2

P Moss - Nature immunology, 2022 - nature.com
The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …

Adaptive immune responses and immunity to SARS-CoV-2

D Primorac, K Vrdoljak, P Brlek, E Pavelić… - Frontiers in …, 2022 - frontiersin.org
Since the onset of the COVID-19 pandemic, the medical field has been forced to apply the
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …

Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection

S Adamo, J Michler, Y Zurbuchen, C Cervia… - Nature, 2022 - nature.com
Immunological memory is a hallmark of adaptive immunity and facilitates an accelerated and
enhanced immune response upon re-infection with the same pathogen,. Since the outbreak …

The robustness of cellular immunity determines the fate of SARS-CoV-2 infection

E Moga, E Lynton-Pons, P Domingo - Frontiers in immunology, 2022 - frontiersin.org
Two years after the appearance of the SARS-CoV-2 virus, the causal agent of the current
global pandemic, it is time to analyze the evolution of the immune protection that infection …

The ins and outs of SARS-CoV-2 variants of concern (VOCs)

M Salehi-Vaziri, M Fazlalipour, SM Seyed Khorrami… - Archives of …, 2022 - Springer
Abstract SARS-CoV-2, a newly emerging coronavirus that caused the COVID-19 epidemic,
has been spreading quickly throughout the world. Despite immunization and some fairly …

[HTML][HTML] Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications

J Majidpoor, K Mortezaee - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a multi-tasking cytokine that represents high activity in patients
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and cancer. High …

Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants

KM Vadrevu, B Ganneru, S Reddy, H Jogdand… - Scientific reports, 2022 - nature.com
This is a comprehensive report on immunogenicity of COVAXIN® booster dose against
ancestral and Variants of Concern (VOCs) up to 12 months. It is well known that neutralizing …

Heterogenous humoral and cellular immune responses with distinct trajectories post-SARS-CoV-2 infection in a population-based cohort

D Menges, KD Zens, T Ballouz, N Caduff… - Nature …, 2022 - nature.com
To better understand the development of SARS-CoV-2-specific immunity over time, a
detailed evaluation of humoral and cellular responses is required. Here, we characterize …

[HTML][HTML] SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents

P Garcia-Valtanen, CM Hope, MG Masavuli… - Cell Reports …, 2022 - cell.com
Summary Coronavirus disease 2019 (COVID-19) convalescents living in regions with low
vaccination rates rely on post-infection immunity for protection against re-infection with …

Booster dose of mRNA vaccine augments waning T cell and antibody responses against SARS-CoV-2

FG Özbay Kurt, A Lepper, C Gerhards… - Frontiers in …, 2022 - frontiersin.org
A gradual decay in humoral and cellular immune responses over time upon SAR1S-CoV-2
vaccination may cause a lack of protective immunity. We conducted a longitudinal analysis …