DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders
Naked mole rats (NMRs) live an exceptionally long life, appear not to exhibit age-related
decline in physiological capacity and are resistant to age-related diseases. However, it has …
decline in physiological capacity and are resistant to age-related diseases. However, it has …
The influence of diet on metabolism and health across the lifespan in nonhuman primates
EK Wood, EL Sullivan - Current opinion in endocrine and metabolic …, 2022 - Elsevier
The macro and micronutrient composition and the overall quantity of the diet are important
predictors of physical and psychological health and, as a consequence, behavior …
predictors of physical and psychological health and, as a consequence, behavior …
Transcriptional profiles in olfactory pathway–associated brain regions of African green monkeys: Associations with age and Alzheimer's disease neuropathology
JD Negrey, DL Dobbins, TD Howard… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction Olfactory impairment in older individuals is associated with an increased risk of
Alzheimer's disease (AD). Characterization of age versus neuropathology‐associated …
Alzheimer's disease (AD). Characterization of age versus neuropathology‐associated …
Divergent age-related methylation patterns in long and short-lived mammals
Age-related changes to cytosine methylation have been extensively characterized across
the mammalian family. Some cytosines that are conserved across mammals exhibit age …
the mammalian family. Some cytosines that are conserved across mammals exhibit age …
Genome-wide DNA methylation profile indicates potential epigenetic regulation of aging in the rhesus macaque thymus
H Qiu, H Li, R Fan, Y Song, X Pan, C Zhang… - International Journal of …, 2022 - mdpi.com
We analyzed whole-genome bisulfite sequencing (WGBS) and RNA sequencing data of two
young (1 year old) and two adult (9 years old) rhesus macaques (Macaca mulatta) to …
young (1 year old) and two adult (9 years old) rhesus macaques (Macaca mulatta) to …
A deep neural network provides an ultraprecise multi-tissue transcriptomic clock for the short-lived fish Nothobranchius furzeri and identifies predicitive genes …
E Ferrari, K Reichwald, P Koch, M Groth, M Baumgart… - bioRxiv, 2022 - biorxiv.org
A key and unresolved question in aging research is how to quantify aging at the individual
level that led to development of” aging clocks”, machine learning algorhythms trained to …
level that led to development of” aging clocks”, machine learning algorhythms trained to …