Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment
Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis,
and drug resistance. However, the mechanisms underlying these associations are largely …
and drug resistance. However, the mechanisms underlying these associations are largely …
GADD45B predicts lung squamous cell carcinoma survival and impacts immune infiltration, and T cell exhaustion
Y Lv, Z Liu, K Xiong, H Duan, J Yang, P Liao - Autoimmunity, 2023 - Taylor & Francis
Background: This study focussed on exploring the prognostic prediction performance of the
growth arrest and DNA damage-inducible 45 beta (GADD45B) and its associations with T …
growth arrest and DNA damage-inducible 45 beta (GADD45B) and its associations with T …
COL5A2 is a prognostic-related biomarker and correlated with immune infiltrates in gastric cancer based on transcriptomics and single-cell RNA sequencing
M Chen, X Zhu, L Zhang, D Zhao - BMC Medical Genomics, 2023 - Springer
Background There is still a therapeutic challenge in treating gastric cancer (GC) due to its
high incidence and poor prognosis. Collagen type V alpha 2 (COL5A2) is increased in …
high incidence and poor prognosis. Collagen type V alpha 2 (COL5A2) is increased in …
Systematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer
Y Yu, Y Sun, Z Li, J Li, D Tian - BMC bioinformatics, 2023 - Springer
Background XRCC4 is a NHEJ factor identified recently that plays a vital role in repairing
DNA double-stranded breaks. Studies have reported the associations between abnormal …
DNA double-stranded breaks. Studies have reported the associations between abnormal …
EZH2 as a prognostic-related biomarker in lung adenocarcinoma correlating with cell cycle and immune infiltrates
K Fan, B Zhang, D Han, Y Sun - BMC bioinformatics, 2023 - Springer
Backgrounds It has been observed that high levels of enhancer of zeste homolog 2 (EZH2)
expression are associated with unsatisfactory prognoses and can be found in a wide range …
expression are associated with unsatisfactory prognoses and can be found in a wide range …
Urothelial bladder cancer: genomic alterations in fibroblast growth factor receptor
M Bou Zerdan, G Bratslavsky, J Jacob, J Ross… - Molecular Diagnosis & …, 2023 - Springer
Abstract Background and Objective Genomic alterations in fibroblast growth factor receptor
(FGFR) genes have been linked to a reduced response to immune checkpoint inhibitors …
(FGFR) genes have been linked to a reduced response to immune checkpoint inhibitors …
Comprehensive analysis of fatty acid metabolism-related gene signatures for predicting prognosis in patients with prostate cancer
H Wang, Z Liu, Y Wang, D Han, Y Du, B Zhang, Y He… - PeerJ, 2023 - peerj.com
Fatty acid metabolism (FAM) is an important factor in tumorigenesis and development.
However, whether fatty acid metabolism (FAM)-related genes are associated with prostate …
However, whether fatty acid metabolism (FAM)-related genes are associated with prostate …
[HTML][HTML] Immune responses of six-transmembrane epithelial antigen of the prostate 4 functions as a novel biomarker in gastric cancer
ZX Fang, YY Hou, Z Wu, BX Wu, Y Deng… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Immune cells play an important role in regulating the behavior of tumor
cells. According to emerging evidence, six-transmembrane epithelial antigen of the prostate …
cells. According to emerging evidence, six-transmembrane epithelial antigen of the prostate …
FZD6 promotes melanoma cell invasion but not proliferation by regulating canonical wnt signaling and epithelial‒mesenchymal transition
B Dong, L Simonson, S Vold, E Oldham… - Journal of Investigative …, 2023 - Elsevier
FZD6 is a key gene that controls tissue polarity during development. Increasing evidence
suggests that it also plays active roles in various cancers. In this study, we show that FZD6 is …
suggests that it also plays active roles in various cancers. In this study, we show that FZD6 is …
Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of …
M Meng, R Gao, Z Liu, F Liu, S Du, Y Song… - Frontiers in …, 2023 - frontiersin.org
Background: Acting as a viral entry for coronavirus to invade human cells, TMPRSS2 has
become a target for the prevention and treatment of COVID-19 infection. Before this …
become a target for the prevention and treatment of COVID-19 infection. Before this …