The plasticitome of cortical interneurons

AR McFarlan, CYC Chou, A Watanabe… - Nature Reviews …, 2023 - nature.com
Hebb postulated that, to store information in the brain, assemblies of excitatory neurons
coding for a percept are bound together via associative long-term synaptic plasticity. In this …

[PDF][PDF] Hippocampal GABAergic interneurons and memory

A Tzilivaki, JJ Tukker, N Maier, P Poirazi, RP Sammons… - Neuron, 2023 - cell.com
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

[HTML][HTML] High ventilation breathwork practices: An overview of their effects, mechanisms, and considerations for clinical applications

GW Fincham, A Kartar, MV Uthaug, B Anderson… - Neuroscience & …, 2023 - Elsevier
Abstract High Ventilation Breathwork (HVB) refers to practices employing specific volitional
manipulation of breathing, with a long history of use to relieve various forms of psychological …

Dysfunction of NRG1/ErbB4 signaling in the Hippocampus might mediate long-term memory decline after systemic inflammation

Y Gao, X Wu, Z Zhou, P Liu, J Yang, M Ji - Molecular Neurobiology, 2023 - Springer
Accumulating evidence has suggested that a great proportion of sepsis survivors suffer from
long-term cognitive impairments after hospital discharge, leading to decreased life quality …

[HTML][HTML] Large-scale integration of single-cell RNA-Seq data reveals astrocyte diversity and transcriptomic modules across six central nervous system disorders

Z Qian, J Qin, Y Lai, C Zhang, X Zhang - Biomolecules, 2023 - mdpi.com
The dysfunction of astrocytes in response to environmental factors contributes to many
neurological diseases by impacting neuroinflammation responses, glutamate and ion …

Neuregulin4 acts on hypothalamic ErBb4 to excite oxytocin neurons and preserve metabolic homeostasis

Y Zhang, Y Zhu, J Wang, L Jin, M Guo… - Advanced …, 2023 - Wiley Online Library
Abstract Neuregulin 4 (Nrg4) is an adipose tissue‐enriched secreted factor that modulates
glucose and lipid metabolism. Nrg4 is closely associated with obesity and preserves diet …

[HTML][HTML] Genetic labeling reveals spatial and cellular expression pattern of neuregulin 1 in mouse brain

CY Ding, YT Ding, H Ji, YY Wang, X Zhang, DM Yin - Cell & Bioscience, 2023 - Springer
Background Where the gene is expressed determines the function of the gene. Neuregulin 1
(Nrg1) encodes a tropic factor and is genetically linked with several neuropsychiatry …

Prenatal dexamethasone exposure induces anxiety-and depressive-like behavior of male offspring rats through intrauterine programming of the activation of NRG1 …

S Zhang, S Hu, W Dong, S Huang, Z Jiao, Z Hu… - Cell Biology and …, 2023 - Springer
Dexamethasone is a commonly used synthetic glucocorticoid in the clinic. As a compound
that can cross the placental barrier to promote fetal lung maturation, dexamethasone is …

[PDF][PDF] An inhibitory circuit-based enhancer of Dyrk1a function reverses Dyrk1a-associated impairment in social recognition

YT Shih, JB Alipio, A Sahay - Neuron, 2023 - cell.com
Heterozygous mutations in the dual-specificity tyrosine phosphorylation-regulated kinase 1a
(Dyrk1a) gene define a syndromic form of autism spectrum disorder. The synaptic and circuit …

[HTML][HTML] Interneuron odyssey: molecular mechanisms of tangential migration

I Toudji, A Toumi, É Chamberland… - Frontiers in Neural …, 2023 - ncbi.nlm.nih.gov
Cortical GABAergic interneurons are critical components of neural networks. They provide
local and long-range inhibition and help coordinate network activities involved in various …