Is endothelial activation a critical event in thrombotic thrombocytopenic purpura?
R Cauchois, R Muller, M Lagarde… - Journal of Clinical …, 2023 - mdpi.com
Thrombotic thrombocytopenic purpura (TTP) is a severe thrombotic microangiopathy. The
current pathophysiologic paradigm suggests that the ADAMTS13 deficiency leads to Ultra …
current pathophysiologic paradigm suggests that the ADAMTS13 deficiency leads to Ultra …
Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome
B Simbrunner, IF Villesen, B Scheiner… - Hepatology …, 2023 - Springer
Background and aims Endothelial dysfunction and portal hypertension (PH) are reflected by
increased von Willebrand factor antigen (VWF-Ag) levels in advanced chronic liver disease …
increased von Willebrand factor antigen (VWF-Ag) levels in advanced chronic liver disease …
[HTML][HTML] Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor
E Elsheikh, M Lavin, LA Heck, N Larkin… - Journal of Thrombosis …, 2023 - Elsevier
Background Previous studies have reported marked interindividual variation in factor VIII
(FVIII) clearance in patients with hemophilia (PWH) and proposed a number of factors that …
(FVIII) clearance in patients with hemophilia (PWH) and proposed a number of factors that …
Systematic review and meta-analysis of within-subject and between-subject biological variation data of coagulation and fibrinolytic measurands
MJ Hollestelle, AH Kristoffersen, RN Idema… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives The diagnosis and monitoring of bleeding and thrombotic disorders depend on
correct haemostatic measurements. The availability of high-quality biological variation (BV) …
correct haemostatic measurements. The availability of high-quality biological variation (BV) …
[HTML][HTML] Quantitative super-resolution imaging of platelet degranulation reveals differential release of von Willebrand factor and von Willebrand factor propeptide from …
M Swinkels, S Hordijk, PE Bürgisser, JA Slotman… - Journal of Thrombosis …, 2023 - Elsevier
Abstract Background Von Willebrand factor (VWF) and VWF propeptide (VWFpp) are stored
in eccentric nanodomains within platelet alpha-granules. VWF and VWFpp can undergo …
in eccentric nanodomains within platelet alpha-granules. VWF and VWFpp can undergo …
[HTML][HTML] Enhanced thrombin generation potential and endothelial dysfunction in chronic spontaneous urticaria
K Ridge, H Fogarty, D Doherty, M Byrne… - Clinical and …, 2023 - ncbi.nlm.nih.gov
To the Editor, Chronic spontaneous urticaria (CSU) is characterized by recurrent hives that
last longer than 6 weeks. The relationship between the coagulation cascade, endothelial …
last longer than 6 weeks. The relationship between the coagulation cascade, endothelial …