The multiple roles of life stress in metabolic disorders
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …
excessive stress can damage body functions. We review current evidence from basic …
The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health
CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …
[HTML][HTML] Age-related social selectivity: An adaptive lens on a later life social phenotype
Age-related social selectivity is a process in which older humans reduce their number of
social partners to a subset of positive and emotionally fulfilling relationships. Although …
social partners to a subset of positive and emotionally fulfilling relationships. Although …
Ecological validity of social defeat stressors in mouse models of vulnerability and resilience
DM Lyons, S Ayash, AF Schatzberg… - … & Biobehavioral Reviews, 2023 - Elsevier
Laboratory mouse models offer opportunities to bridge the gap between basic neuroscience
and applied stress research. Here we consider the ecological validity of social defeat …
and applied stress research. Here we consider the ecological validity of social defeat …
Contextual modifiers of healthspan, lifespan, and epigenome in mice under chronic social stress
Sustained life stress and low socioeconomic status are among the major causes of aging-
related diseases and decreased life expectancy. Experimental rodent models can help to …
related diseases and decreased life expectancy. Experimental rodent models can help to …
Re-wilding Model Organisms: Opportunities to test causal mechanisms in social determinants of health and aging
Social experiences are strongly associated with individuals' health, aging, and survival in
many mammalian taxa, including humans. Despite their role as models of many other …
many mammalian taxa, including humans. Despite their role as models of many other …
The biology of aging in a social world: Insights from free-ranging rhesus macaques
Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long …
biological mechanisms that link social adversities to aging remain poorly understood. Long …
Intergenerational differences on resilience, sense of coherence, and self-efficacy coping of family during COVID19 crisis: A salutogenic perspective
IT Angeles, RG Perkins - Current Psychology, 2023 - Springer
The COVID-19 pandemic has afflicted people from all sectors of life, and families have faced
unprecedented challenges. In this study, researchers explore how intergenerational …
unprecedented challenges. In this study, researchers explore how intergenerational …
Social buffering reduces hair cortisol content in black-tailed prairie dogs during reproduction
Stressors activate the hypothalamic-pituitary-adrenal axis which produces glucocorticoid
(GC) hormones. Social buffering, the lowering of glucocorticoid secretion with increased …
(GC) hormones. Social buffering, the lowering of glucocorticoid secretion with increased …
[HTML][HTML] Post craniotomy pain management in Copenhagen rat by intraperitoneal or oral dosage of Tramadol: a comparative evaluation
Calvarial craniotomy in animal models involves pain and distress. Moderate to severe pain
in laboratory animals requires adequate pain management strategies. According to previous …
in laboratory animals requires adequate pain management strategies. According to previous …