In recent years, genome-wide association studies (GWAS) have been instrumental in unraveling the genetic architecture of complex diseases, including psoriasis. The application …
B Frost, M Schmidt, B Klein… - European Journal of …, 2023 - Wiley Online Library
Rationale Psoriasis is a chronic inflammatory skin disease involving different cytokines and chemokines. Objectives Here we use single‐cell transcriptomic analyses to identify relevant …
Y Jeong, J Song, Y Lee, E Choi, Y Won, B Kim… - International Journal of …, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by cutaneous eruptions and pruritus. Because the genetic backgrounds of psoriasis are only partially revealed, an …
Q Xiao, J Mears, A Nathan, K Ishigaki… - Nature …, 2023 - nature.com
Psoriasis is a chronic, systemic inflammatory condition primarily affecting skin. While the role of the immune compartment (eg, T cells) is well established, the changes in the skin …
A Czarnecka, D Purzycka-Bohdan, M Zabłotna… - Genes, 2023 - mdpi.com
Psoriasis comorbidities may emerge from pleiotropic mechanisms, including common proinflammatory pathways, cellular mediators or genetic predisposition. Obesity is …
F Zhou, S Wang, H Qin, H Zeng, J Ye, J Yang, G Cai… - BMC genomics, 2023 - Springer
Background Aplasia cutis congenita (ACC) is a rare genetic disorder characterized by the localized or widespread absence of skin in humans and animals. Individuals with ACC may …
Psoriasis is a dermatologic disease that affects 2% of the world population. Psoriasis is characterized by chronic inflammation and aberrant behavior of keratinocytes, which display …
X Xie, L Zhang, Y Lin, X Liu, N Wang, P Li - PeerJ, 2023 - peerj.com
Background Psoriasis is an autoimmune skin disease characterized by immunocyte activation, excessive proliferation, and abnormal differentiation of keratinocytes. Signal …
B Dai, Y Bai, HD Yu, Q Huang… - Clinical, Cosmetic and …, 2023 - Taylor & Francis
Although psoriasis and systemic lupus erythematosus are both immune abnormalities, there are few reports on Ps combined with SLE in China and abroad. We present a case of a 23 …