The roles and implications of RNA m6A modification in cancer
Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
Molecular mechanisms of environmental exposures and human disease
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …
environmental exposures and pollutants. An appreciation of how environmental pollutants …
[HTML][HTML] Small RNA modifications: regulatory molecules and potential applications
Q Xiong, Y Zhang - Journal of Hematology & Oncology, 2023 - Springer
Small RNAs (also referred to as small noncoding RNAs, sncRNA) are defined as polymeric
ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of …
ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of …
[HTML][HTML] Crosstalk between N6-methyladenosine (m6A) modification and noncoding RNA in tumor microenvironment
D Wang, Y Han, L Peng, T Huang, X He… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is the most abundant RNA modification in eukaryotes,
and it participates in the regulation of pathophysiological processes in various diseases …
and it participates in the regulation of pathophysiological processes in various diseases …
Super-enhancer RNA m6A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinoma
R Li, H Zhao, X Huang, J Zhang, R Bai, L Zhuang… - Nature Genetics, 2023 - nature.com
The biological functions of noncoding RNA N 6-methyladenosine (m6A) modification remain
poorly understood. In the present study, we depict the landscape of super-enhancer RNA …
poorly understood. In the present study, we depict the landscape of super-enhancer RNA …
METTL3 promotes pancreatic cancer proliferation and stemness by increasing stability of ID2 mRNA in a m6A-dependent manner
J Chen, H Zhang, C Xiu, C Gao, S Wu, J Bai, Q Shen… - Cancer Letters, 2023 - Elsevier
Abstract In eukaryotes, N 6-methyladenosine (m6A) is the most prevalent epigenetic
alteration. Methyltransferase-like 3 (METTL3) is a key player in the control of m6A, although …
alteration. Methyltransferase-like 3 (METTL3) is a key player in the control of m6A, although …
Effects of writers, erasers and readers within miRNA‐related m6A modification in cancers
H Feng, X Yuan, S Wu, Y Yuan, L Cui, D Lin… - Cell …, 2023 - Wiley Online Library
Background As one of the most abundant post‐transcriptional mRNA modifications, N6‐
methyladenosine (m6A) has attracted extensive attention from scientists. Emerging evidence …
methyladenosine (m6A) has attracted extensive attention from scientists. Emerging evidence …
N6-methyladenosine in macrophage function: a novel target for metabolic diseases
X Zhu, HJ Tang, M Yang, K Yin - Trends in Endocrinology & Metabolism, 2023 - cell.com
Abstract N6-methyladenosine (m 6 A) is one of the most prevalent internal transcriptional
modifications. Evidence has highlighted changes in m 6 A in metabolic disorders and …
modifications. Evidence has highlighted changes in m 6 A in metabolic disorders and …
[HTML][HTML] Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
Y Xu, Y Zhang, Y Luo, G Qiu, J Lu, M He… - Cell Death Discovery, 2023 - nature.com
Abstract N6-methyladenosine (m6A) modification, catalyzed by methyltransferase
complexes (MTCs), plays many roles in multifaceted biological activities. As the most …
complexes (MTCs), plays many roles in multifaceted biological activities. As the most …
Roles and implications of mRNA N6‐methyladenosine in cancer
RNA N6‐methyladenosine modification is the most prevalent internal modification of
eukaryotic RNAs and has emerged as a novel field of RNA epigenetics, garnering increased …
eukaryotic RNAs and has emerged as a novel field of RNA epigenetics, garnering increased …